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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 11, No. 1, 2014, pp. 93-96
Bioline Code: tc14013
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 11, No. 1, 2014, pp. 93-96

 en PRELIMINARY EXAMINATION OF HERBAL EXTRACTS ON THE INHIBITION OF HELICOBACTER PYLORI check for this species in other resources
Guzeldag, Gulcihan; Kadioglu, Lutfiye; Mercimek, Aysun & Matyar, Fatih

Abstract

Background: This work aims at describing the traditional uses, to determine the antimicrobial potential of two different extracts hexane, acetone of the leaves of Citrus unshiu check for this species in other resources , Citrus sinensis check for this species in other resources , Citrus limon check for this species in other resources , Laurus nobilis check for this species in other resources , Citrus paradisi check for this species in other resources on clinical strain of H. pylori check for this species in other resources in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. H. pylori strain was a culture collection of Hacettepe University, Turkey. Methods: The activity was quantitatively assessed on the basis of the inhibition zone, and their activity index was also calculated along with the MIC method.
Results: All the plants demonstrated antimicrobial activity against H. pylori with zone of inhibition diameters ranging from 0 - 30 mm and minimum inhibitory concentration (MIC) values ranging from 1:512- 1:4096 dilutions.
Conclusion: The results may serve as scientific validation of the ethnomedicinal uses of the Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis, and Citrus paradisi in the treatment of H. pylori-related infections. However, further investigations would be necessary to determine their toxicological properties, in-vivo potencies and mechanism of action against H. pylori.

Keywords
Helicobacter pylori; antimicrobial activity; plant extracts; acetone; hexane; MIC

 
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