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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 11, No. 1, 2014, pp. 116-120
Bioline Code: tc14017
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 11, No. 1, 2014, pp. 116-120

 en A STUDY ON ANTIMICROBIAL, ANTIOXIDANT AND ANTIMUTAGENIC ACTIVITIES OF ELAEAGNUS ANGUSTIFOLIA check for this species in other resources L. LEAVES
Okmen, G. & Turkcan, O.

Abstract

Background: The aim of this work was to investigate the antimicrobial, antioxidant, and antimutagenic potentials of methanol extracts from E. angustifolia check for this species in other resources .
Materials and Methods: Methanol extracts were screened for antimicrobial activity against different species of 4 Gram positive and 3 Gram negative bacteria and one fungus. These bacteria included food pathogens. The leaf extract was tested using disc diffusion assay.
Results: The methanol extract of E. angustifolia showed maximum inhibition zone of 16 mm against Yersinia enterocolitica check for this species in other resources . Whereas, the inhibition zone was not determined by methanol extract against Escherichia coli check for this species in other resources ATCC 1122 and Candida albicans check for this species in other resources RSKK 02029. The MIC was evaluated on plant extracts as antimicrobial activity. All of bacterial strains showed the lowest sensitivity to methanol extract of E. angustifolia (3.5 mg/mL), except Yersinia enterocolitica NCTC 11174. In addition, the plant extracts were tested against the stable DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free-radical. Finally, the methanol extract displayed a strong antioxidant activity (Trolox equivalent = 1.49 mM). Also, E. angustifolia methanol extracts were screened for their antimutagenic activity against sodium azide by Ames test in absence of rat microsomal liver enzyme (-S9). The results showed that E. angustifolia methanol extracts can inhibit mutagenic agents of sodium azide. The plant leaf extracts with the inhibition of 36% sodium azide showed moderate potential in decreasing mutagenic agents in Salmonella typhimurium check for this species in other resources TA100.
Conclusion: E. angustifolia methanol extracts have antimicrobial, antioxidant and antimutagenic potential.

Keywords
Elaeagnus; antimicrobial activity; antioxidant activity; antimutagenic activity

 
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