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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 11, No. 6, 2014, pp. 118-126
Bioline Code: tc14170
Full paper language: English
Document type: Review Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 11, No. 6, 2014, pp. 118-126

 en A REVIEW OF THE PHYTOCHEMISTRY, BOTANY, PHARMACOLOGY AND TOXICOLOGY OF ARCTOTIS ARCTOTOIDES check for this species in other resources (L.F.) O. HOFFM. (ASTERACEAE)
Grierson, Donald Scott; Otang, Wilfred Mbeng & Afolayan, Anthony Jide

Abstract

Background: Arctotis arctotoides check for this species in other resources (Asteraceae) is commonly used by the rural people of Eastern Cape for the treatment of epilepsy, indigestion, catarrh and stomach ache. The leaf paste or juice is applied topically in the treatment of wounds and skin disorders. Unfortunately, no previous reviews are available for this important medicinal plant. Hence, the aim of this review is to provide a comprehensive overview of the botany, phytochemistry, pharmacology and toxicology of Arctotis arctotoides.
Methodology: This review was carried out using a comprehensive and systematic literature search on the following databases: Google Scholar, PubMed, Science Direct and Scopus. Searches were undertaken using the key word “Arctotis arctotoides” and the six synonyms of Arctotis arctotoides identified in the Plant List.
Results: In the first phyto-chemical study of Arctotis arctotoides, the authors reported that sesquiterpenoids presence was predominant in the root oil whereas, the essential oils of the leaves, flowers and stems had both monoterpenoids and sesquiterpenoids. The literature survey revealed that Arctotis arctotoides has been investigated in four pharmacological areas, including anti-bacterial, anti-fungal, anti-cancer and anti-oxidant activities. Three toxicity screens for the crude extracts of A. arctotoides on cell lines, rats and brine shrimp were identified in the literature.
Conclusion: Detailed studies on the bioactivity of the crude extracts and the isolated phyto-chemicals have provided partial evidence as regards the traditional use of A. arctotoides in the treatment of wounds in Eastern Cape of South Africa. However, in order to fully exploit the medicinal potential of A. arctotoides, the expansion of existing traditional knowledge into neighboring communities where the plant is not currently in use for the stated indications will support a greater use of the plant in primary healthcare.

Keywords
Arctotis arctotoides; botany; phyto-chemistry; pharmacology and toxicology

 
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