Background: H. bacciferum
belonging to the family Boraginaceae is an important medicinal plant. The current research was carried out to investigate
the medicinal properties of this plant.
Methodology: The crude (methanol fraction) and n-hexane, ethyl acetate, butanol and aqueous fractions were subjected to antibacterial and antifungal
activities by using standard methodology available in literature. Bacterial strains of
Salmonella typhi
,
Escherichia coli
,
Pseudomonas Aeroginosa
,
Staphylococcus aureus
,
Erwinia carotovora
,
Klebsiella Pneumoniae
,
Bacillus subtilis
and
Bacillus atrophaeus
were used for antibacterial activity.
Results: All the fractions were active against different bacterial strains but n-hexane and ethyl acetate showed (Zone of inhibition ranged from 18-30
mm) highest activity. The fungal strains,
Trichoderma longibrachiantum
,
Aspergillus flavus
,
Aspergillus niger
,
Fusarium solani
and
Candida albican
were used for antifungal activity. Excellent inhibitory effect was observed against all fungal strains. The minimum inhibitory concentration (MIC)
against various fungal strains was determined. The minimum inhibitory concentrations (MICs) of the investigated plant fractions ranged from 0.5-
2.00 mg/ml.
Conclusion: The plant showed significant antibacterial and antifungal activities. All tested plant extracts exhibit activities against different fungal
strains. The result against various microorganisms shows the therapeutic potential of the plant
H. bacciferum 
