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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 12, No. 2, 2015, pp. 32-35
Bioline Code: tc15025
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 12, No. 2, 2015, pp. 32-35

 en ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF THE EXTRACT AND FRACTIONS OF AERIAL PARTS OF HELIOTROPIUM BACCIFERUM check for this species in other resources
Ahmad, Shabir; Ahmad, Sohail; bibi, Ihteram; AbdEl-Salam, Naser M.; Hussain, Hidayat; Ishaq, Muhammad Saqib; Adnan, Muhammad; Tariq, Akash & Ullah, Riaz

Abstract

Background: H. bacciferum check for this species in other resources belonging to the family Boraginaceae is an important medicinal plant. The current research was carried out to investigate the medicinal properties of this plant.
Methodology: The crude (methanol fraction) and n-hexane, ethyl acetate, butanol and aqueous fractions were subjected to antibacterial and antifungal activities by using standard methodology available in literature. Bacterial strains of Salmonella typhi check for this species in other resources , Escherichia coli check for this species in other resources , Pseudomonas Aeroginosa check for this species in other resources , Staphylococcus aureus check for this species in other resources , Erwinia carotovora check for this species in other resources , Klebsiella Pneumoniae check for this species in other resources , Bacillus subtilis check for this species in other resources and Bacillus atrophaeus check for this species in other resources were used for antibacterial activity.
Results: All the fractions were active against different bacterial strains but n-hexane and ethyl acetate showed (Zone of inhibition ranged from 18-30 mm) highest activity. The fungal strains, Trichoderma longibrachiantum check for this species in other resources , Aspergillus flavus check for this species in other resources , Aspergillus niger check for this species in other resources , Fusarium solani check for this species in other resources and Candida albican check for this species in other resources were used for antifungal activity. Excellent inhibitory effect was observed against all fungal strains. The minimum inhibitory concentration (MIC) against various fungal strains was determined. The minimum inhibitory concentrations (MICs) of the investigated plant fractions ranged from 0.5- 2.00 mg/ml. Conclusion: The plant showed significant antibacterial and antifungal activities. All tested plant extracts exhibit activities against different fungal strains. The result against various microorganisms shows the therapeutic potential of the plant H. bacciferum

Keywords
H. bacciferum; Medicinal Plant; crude fractions; Antimicrobial activities

 
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