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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 12, No. 3, 2015, pp. 104-112
Bioline Code: tc15055
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 12, No. 3, 2015, pp. 104-112

 en SCREENING FOR ANTIBACTERIAL AND ANTIPROTOZOAL ACTIVITIES OF CRUDE EXTRACTS DERIVED FROM MEXICAN MEDICINAL PLANTS
Camacho-Corona, María del Rayo; García, Abraham; Mata-Cárdenas, Benito D.; Garza-González, Elvira; Ibarra-Alvarado, César; Rojas-Molina, Alejandra; Rojas-Molina, Isela; Bah, Moustapha; Sánchez, Miguel Angel Zavala & Gutiérrez, Salud Pérez

Abstract


Background: Crataegus mexicana check for this species in other resources , Hyptis albida, Larrea tridentata check for this species in other resources ,Ocimum baislicum, Prunus serotina check for this species in other resources , and Smilax check for this species in other resources spp. are used in Mexican traditional medicine to treat respiratory and gastrointestinal diseases such as flu, cough, diarrhea, dysentery, and other parasitic or microbial infections. Therefore this study was aimed at the pharmacological prospection of these plants against eleven bacterial species and three amitochondrial protist pathogens.
Material and methods: The fruits or aerial parts of C. mexicana, H. albida, L. tridentata, O. baislicum, P. serotina, and Smilax spp. were extracted with different solvents. The antibacterial properties of organic and aqueous extracts of these plants were determined by the microdilution method and the microplate alamar blue assay against Stenotrophomonas maltophilia check for this species in other resources , Escherichia coli check for this species in other resources , Acinetobacter baumannii check for this species in other resources , Pseudomonas aeruginosa check for this species in other resources , Klebsiella pneumoniae check for this species in other resources , Enterobacter cloacae check for this species in other resources , Staphylococcus aureus check for this species in other resources , methicillin-resistant S. aureus, Listeria monocytogenes check for this species in other resources , Enterococcus faecalis check for this species in other resources , and Mycobacterium tuberculosis check for this species in other resources , whereas anti-protozoal activities of extracts were evaluated by a vial micro-assay against strains of Entamoeba histolytica check for this species in other resources , Trichomonas vaginalis, and Giardia lamblia check for this species in other resources .
Results: H. albida, Smilax spp, and C. mexicana showed good activity against the Gram-positive strains, S. aureus, methicillin-resistant S. aureus, and E. faecalis. Four extracts (C. mexicana, H. albida, O. basilicum, and L. tridentata) showed good activity against E. histolytica, T. vaginalis, and G. lamblia.
Conclusion: The extracts of these six medicinal plants could be a source for new antibacterial and antiprotozoal drugs. For this reason they are currently under investigation to isolate and characterize their active compounds.

Keywords
antibacterial; antiprotozoal; extract; plants; traditional medicine

 
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