Background: Astragaloside III has been used to treat different cancers; however their effect on breast cancer remains unknown.
Materials and methods: The present study examined the effects of Astragaloside III from
Astragalus membranaceus
on breast cancer cell lines
in vitro as well as xenograft in vivo.
Results: The results showed that the Astragaloside III could effectively reduce cancer cell survival
in vitro and inhibit the tumor growth
in vivo.
The potential mechanism is the induction of cell apoptosis signaling pathways.
Conclusion: We believe that Astragaloside III provides a new therapeutic tool to treat breast cancer.
