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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 12, No. 3, 2015, pp. 183-186
Bioline Code: tc15065
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 12, No. 3, 2015, pp. 183-186

 en ASTRAGALOSIDE III FROM ASTRAGALUS MEMBRANACEUS check for this species in other resources ANTAGONIZES BREAST CANCER GROWTH
Wang, Shouman; Tang, Lili & Chen, Feiyu

Abstract


Background: Astragaloside III has been used to treat different cancers; however their effect on breast cancer remains unknown.
Materials and methods: The present study examined the effects of Astragaloside III from Astragalus membranaceus check for this species in other resources on breast cancer cell lines in vitro as well as xenograft in vivo.
Results: The results showed that the Astragaloside III could effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo. The potential mechanism is the induction of cell apoptosis signaling pathways.
Conclusion: We believe that Astragaloside III provides a new therapeutic tool to treat breast cancer.

Keywords
breast cancer; Astragaloside III; apoptosis; treatment

 
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