Background: Albuca bracteata
is a medicinal plant traditionally used in the management of diabetes mellitus in the Eastern Cape of South
Africa. The purpose of this study was to evaluate the antioxidant and anti-inflammatory activities of saponins extracted from the bulb of Albuca
and compared with the crude methanolic extract.
Methods: In vitro
antioxidant activity was determined using free radical scavenging assays such as DPPH, ABTS and NO2
. The antiinflammatory
potential was carried out using inhibition of protein denaturation of egg albumin as a model of anti-inflammatory capacity.
Both the crude methanolic extract and saponins showed inhibition of DPPH, ABTS and NO2
scavenging activity. However, the free
radical scavenging activity of isolated saponin compared favourably with Rutin and BHT. The crude methanolic extract showed higher
inhibition percentage of protein denaturation compared with the saponins at the concentration investigated.
This study indicates that saponin from Albuca bracteata
bulb possess potent anti-inflammatory activity and is also a good source of