ACTIVATION OF DIFFERENT CEREBRAL FUNCTIONAL REGIONS FOLLOWING ACUPUNCTURE AT BOTH TAIXI AND TAICHONG ACUPOINTS AND TAIXIACUPOINT ALONE: AN FMRI STUDY|
Wang, Y. J.; Zheng, Y.; Zhang, G. F.; Zhang, J. P.; Wu, C. X.; Zhang, S. Q.; Ouyang, H. L.; Li, Z. P.; Chen, J. R.; Qu, S. S.; Chen, J. Q.; Huang, Y. & Tang, C. Z.
Background: To explore the brain function regions characteristics of the acupoint combination, this study observed activity changes in the brain
regions of healthy volunteers after acupuncture at both Taixi (KI3) and Taichong (LR3) (KI3 + LR3) and KI3 alone using resting-state functional
magnetic resonance imaging(fMRI).
Methods: 30 healthy volunteers were randomly allocated into two groups, one group received acupuncture at KI3 and LR3, the other only
acupuncture at KI3, 15 cases in each group. All volunteers underwent resting-state fMRI of the brain 15 minutes before acupuncture, and which
the needle was retained in place for 30 minutes; 15 minutes after withdrawing the needle underwent a further session of resting-state fMRI. The
amplitude of low-frequency fluctuation (ALFF) and regional homogeneity (ReHo) were used to analyze the changes in brain regions.
Results: The KI3+LR3 group compared with the KI3 group, the ALFF analysis indicated that the brain changes relatively concentrated in BA 2,
3, 7, 8, 9, 10, 18, 19, 20, 31, 32, 40, 46 and the cerebellum posterior lobe, the ReHo analysis indicated that the brain changes relatively
concentrated in BA 4, 6, 7, 10, 11, 18, 19, 20, 21, 22, 31, 40 and the cerebellum posterior lobe.
Conclusion: Based on this study, compared with acupuncture at KI3, acupuncture at KI3 + LR3 which could specifically influence BA 7, 10, 18,
19, 20, 31, 40 and cerebellum posterior lobe, which may be related to synergy mechanism of two acupoints combination treatment.
acupoint combination; acupuncture; resting state; functional magnetic resonance imaging (fMRI); amplitude of low-frequency fluctuation (ALFF); regional homogeneity (ReHo)