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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 13, No. 1, 2016, pp. 123-127
Bioline Code: tc16017
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 13, No. 1, 2016, pp. 123-127

 en ANTIMICROBIAL ACTIVITY OF DRACAENA CINNABARI check for this species in other resources RESIN FROM SOQOTRA ISLAND ON MULTI DRUG RESISTANT HUMAN PATHOGENS
Ansari, Mohammad Javed; Al-Ghamdi, Ahmad; Al-Waili, Noori; Adgaba, Nuru; Khan, Khalid Ali & Amro, Abdulraouf

Abstract

Background: Few studies showed that Dracaena cinnabari check for this species in other resources resin, collected from Soqotra Island, Yemen, has antimicrobial activity. This study is the first to investigate antimicrobial activity of the resin on both antibiotic multi-resistant human pathogens and on poly-microbial culture.
Material and Methods: Antimicrobial activity of ethanolic extract of Dracaena cinnabari resin from Soqotra Island on multidrug resistant Gram-positive and Gram-negative human ATCC standard pathogens and Ascosphaera apis check for this species in other resources , the causal organism of chalkbrood disease of honeybee was studied using the agar disc diffusion method. The minimal inhibitory concentration of extracts was carried out by the broth micro dilution method.
Results: Ethanolic extract of Dracaena cinnabari resin showed a considerable antimicrobial activity against all the pathogens tested. The zone of inhibition were between 4.9-11.5 mm. The most sensitive microbe was Staphylococcus aureus check for this species in other resources and least sensitive was Aspergillus nidulans check for this species in other resources . The minimal inhibitory concentration of the extract against Escherichia. coli check for this species in other resources ATCC 10402, Klebsiella pneumonia check for this species in other resources ATCC 10031, and Staphylococcus aureus ATCC 29212 was 1.25 μg/mL (w/v) and for the other pathogens ( Candida albicans check for this species in other resources ATCC 10231, Salmonella typhimurum check for this species in other resources ATCC 3311 and Pseudomonos aeruginosa check for this species in other resources ATCC 2785) was 2.5 μg/mL (w/v).
Conclusion: Ethanolic extract of Dracaena cinnabari resin has a considerable antimicrobial activity against Gram-positive and Gram-negative human pathogens and fungi. This extract might possess a role in the management of microbial infections in human and honeybee disease.

Keywords
Antimicrobial Activity; Dracaena cinnabari; Human pathogens; Minimum Inhibitory Concentration

 
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