Nephrolithiasis is a severe health problem causing morbidity. Chemolisis, extracorporeal shock wave lithotripsy
(SWL), percutaneous nephrolithotomy (PNL), retrograde ureterorenoscopy (URS), and open and laparoscopic surgery are used for
treatment with various success rates. Medical treatments with fewer complications were investigated thoroughly.
Materials and Methods:
In this study, we evaluated the effects of Persea americana
(avocado) leaves and Viburnum opulus
rose) fruits on nephrolithiasis in an animal model and used 42 rats. The groups received both low and high doses of Persea americana
leaves and Viburnum opulus
fruit ethanol extracts orally for 28 days. These two plants have been used for years in Turkey for their
Avocado and guelder rose increased the urine volume and urine citrate levels, decreased urine cystine and oxalate levels, and
lowered the crystal deposits in kidney tissue. Avocado and guelder rose also prevented oxidant damage and crystal formation in kidney
The two plants that have been used for years for nephrolithiasis treatment in Turkey can safely be used for kidney stones.