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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 13, No. 3, 2016, pp. 133-139
Bioline Code: tc16068
Full paper language: English
Document type: Research Article
Document available free of charge

African Journal of Traditional, Complementary and Alternative Medicines, Vol. 13, No. 3, 2016, pp. 133-139

 en THE EFFECTS OF EXTRACTS OF ATRACTYLODES MACROCEPHALA KOIDZ COMBINED WITH TRANSCUTANEOUS ELECTRICALACUPOINT STIMULATION IN TREATING THE OVARIECTOMIZED FEMALE RATS
Weng, Qing; Cao, Zhu-Feng; Yu, Yan-Wen; Lv, Xiang-Lin; Qu, Fan & Zhou, Jue

Abstract

Background: The present study was to explore the effects of the extracts of Atractylodes macrocephala check for this species in other resources Koidz (EAMK) combined with transcutaneous electrical acupoint stimulation (TEAS) on the ovariectomized female rats.
Materials and Methods: Forty female Sprague-Dawley rats were randomly divided into four groups: sham-operation, model, livial and EAMK+TEAS groups (n=10 in each group). After the individual treatments for 8 weeks ended, the serum levels of estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH), osteocalcin and interleukin-6 (IL-6) were measured with commercial enzyme-linked immunosorbent assay.
Results: We found that in the sham-operation group, the serum E2 and osteocalcin levels were significantly higher, and the serum levels of FSH, LH and IL-6 were markedly lower than those of other groups (P<0.05). No significant differences existed between the livial and EAMK+TEAS groups on the serum E2 and osteocalcin levels (P>0.05), however, the serum FSH and IL-6 levels of EAMK+TEAS group were significantly lower than those of the livial group (P<0.05).
Conclusion: EAMK combined with TEAS has promises in treating the ovariectomized female rats.

Keywords
Extracts of Atractylodes macrocephala Koidz (EAMK); transcutaneous electrical acupoint stimulation (TEAS); osteocalcin; interleukin-6 (IL-6)

 
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