African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
Vol. 14, No. 2, 2017, pp. 1-8
Bioline Code: tc17036
Full paper language: English
Document type: Research Article
Document available free of charge
African Journal of Traditional, Complementary and Alternative Medicines, Vol. 14, No. 2, 2017, pp. 1-8
© Copyright 2017 - African Journal of Traditional, Complementary and Alternative Medicines
ANTIOXIDANT ACTIVITY AND Α -AMYLASE INHIBITORY POTENTIAL OF ROSA CANINA L|
Ben Jemaa, Houda; Ben Jemia, Amani; Khlifi, Sarra; Ben Ahmed, Halima; Ben Slama, Fethi; Benzarti, Anis; Elati, Jalila & Aouidet, Abdallah
Background: Diabetes mellitus is one of the most common endocrinal disorders and medicinal plants continue to play
an important role in the management of this disease. In this study, Rosa canina was investigated for the antioxidant and
α-amylase inhibition activities.
Materials and Methods: Methanolic extract of Rosa canina was investigated for its potential antioxidant activity. The
extracts' total phenolic and flavonoid contents and scavenging capacity for free radicals were evaluated. The α-amylase
inhibition assay was also carried.
Results: Rosa canina extract exhibits a total Phenolic and flavonoid levels respectively (21.918 mg GAE/g and
2.647mg ER/g). The free radical scavenging activity was found to be prominent against DPPH with an IC50 of 0.668
mg/ml and against ABTS with an IC50 of 0.467 mg/ml. Extract showed a significant ferric ion reducing activities with
an IC50 of4.962 mg/ml.
Conclusion: Rosa canina exerted a higher inhibitory activity against α-amylase. The obtained results support the
antidiabetic use of rosa canina.
Rosa canina; α-amylase; hyperglycemia; antioxidant activity; phytochemical profile
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