African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
Vol. 16, No. 1, 2019, pp. 24-33
Bioline Code: tc19003
Full paper language: English
Document type: Research Article
Document available free of charge
African Journal of Traditional, Complementary and Alternative Medicines, Vol. 16, No. 1, 2019, pp. 24-33
© Copyright 2019 - African Journal of Traditional, Complementary and Alternative Medicines
APHRODISIAC EFFECTS OF METHANOLIC LEAF EXTRACT OF PSEUDOPANAX ARBOREUS (ARALIACEAE) (L.F. PHILLIPSON) IN NORMAL MALE RATS|
Besong, Egbe B.; Ateufack, G.; Kamanyi, Albert & Moumbock, Aurelien F.A.
Background: The leaves of Pseudopanax arboreus have been used traditionally for decades as aphrodisiac without
scientific investigation. In this study, the effects of methanolic leaf extract of P. arboreus were evaluated on sexual
behavior of normal male rats.
Materials and Methods: Twenty-eight adult male rats were randomly grouped into 4 groups of 7 rats each. Rats in group 1
were treated with 10 ml/kg body weight distilled water, group 2 rats received 6mg/kg body weight Viagra™, while the rats
in groups 3 and 4 were given 46.5 mg and 93mg/kg body weight respectively of the methanolic extract of the leaves of P.
arboreus. Female rats were made receptive by ovariectomy and subsequent hormonal treatment. Sexual behavior
parameters were monitored on days 1, 7, 14 and 21 by pairing each male rat to a receptive female. Relative weight of sex
organs and hormonal (FSH, LH and testosterone) profile were also determined.
Results: Doses of 46.5 mg/kg and 93 mg/kg, the extract significantly increased the mount and intromission frequencies,
penile licking and relative weight of sex organs and enhanced testosterone production; and significantly reduced mount and
intromission latencies, mean intromission interval, when compared to the distilled water group. The 93 mg/kg body weight
dose prolonged ejaculation latency and reduced post-ejaculatory interval. However, the reference drug, Viagra™ proved
more efficient than the extract.
Conclusion: The methanolic extract of the leaves of P. arboreus possesses aphrodisiac properties which may be due to the
actions of bioactive compounds present in the extract.
Pseudopanax arboreus; sexual behavior; methanolic extract; aphrodisiac.
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