Dioscin was extracted and isolated from
Polygonatum Zanlanscianense
Pamp. The effects of dioscin on HL60, HeLa, H14, and MDA-MB-435 cell lines were studied with the results showing that dioscin dramatically inhibited the growth of the MDA-MB-435, H14, HL60, and HeLa cell lines. The IC
50 of dioscin on these cell lines were 2.6, 0.8, 7.5, and 4.5 μmol/L respectively