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VITAE Academia Biomédica Digital
Centro de Análisis de Imágenes Biomédicas Computarizadas-CAIBC0
ISSN: 1317-987x
No. 55, 2013
Bioline Code: va13022
Full paper language: English
Document type: Research Article
Document available free of charge

VITAE Academia Biomédica Digital, No. 55, 2013

 en Antibiotic Sales Regulation In Venezuela and Bacterial Resistance
Gomes De Andrade, Carlos A. & Alonso, Guillermina

Abstract

The loss of antibiotic efficacy has been attributed mainly to its indiscriminate consumption. To control this problem, sales of some antibiotics in Venezuela were regulated in January 2006, making medical prescription indispensable to acquire them. The aim of this study was to determine the impact of this regulation on bacterial resistance. Antibiotic consumption was expressed in the number of Daily Defined Doses per 1,000 inhabitants per day, calculated with the information from the International Marketing System Health. Bacterial resistance was gotten from the database of the Program for Antimicrobial Bacterial Resistance Surveillance in Venezuela. The connection between both variables was established through correlation analysis. The results show that antibiotic consumption and bacterial resistance have suffered a significant increase after the application of the regulation. It is necessary to amplify its application to all the antibiotics and to improve health care professionals’ education for their adecuate prescription.

Keywords
antibiotics; bacterial resistance; sales regulation

 
 es Regulación de la dispensación de antibióticos en Venezuela y resistencia bacteriana
Gomes De Andrade, Carlos A. & Alonso, Guillermina

Resumen

La pérdida de eficacia de los antibióticos se atribuye principalmente a su consumo indiscriminado. En enero de 2006, en Venezuela, se reguló la dispensación de algunos antibióticos, condicionando su venta a la presentación de la receta médica. En este trabajo se determinó el impacto de esta medida sobre la resistencia bacteriana. El consumo de antibióticos se expresó como el número de Dosis Diarias Definidas/1.000 habitantes/día, calculado con la información suministrada por el International Marketing System Health. La información de resistencia bacteriana se obtuvo del Programa Venezolano de Vigilancia de la Resistencia Bacteriana a los Antimicrobianos. Se realizó análisis de correlación entre las variables. Los resultados demuestran que tanto el consumo como la resistencia bacteriana se incrementaron significativamente durante el período posterior a la regulación. Es necesario ampliar la aplicación de esta medida a todos los antibióticos, así como implementar mejoras en la educación fármaco-terapéutica de los profesionales de la salud.

Palabras-clave
antibióticos; resistencia bacteriana; medidas regulatorias

 
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