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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 25, No. 1, 2004, pp. 53-56
Bioline Code: zr04010
Full paper language: Chinese
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 25, No. 1, 2004, pp. 53-56

 en Effects of Follicle-stimulating Hormone and Estrogen on Development of Embryonic Chicken Germ Cell in Vitro
XIE Mei-na ZHANG Cai-qiao MI Yu-ling ZENG Wei-dong


The proliferation,development and maturation of ovarian germ cells are regulated by multiple hormones,among which gonadotropins play a key role.In this study a germ-somatic cell coculture model of 18-day-old chicken embryo ovarian cells was established to evaluate effects of follicle-stimulating hormone (FSH) and 17β-estradiol (E2) alone or in combination on germ cell proliferation.Results showed that FSH (0.25-1 IU/mL) and E2(10-1000 ng/mL) both showed an notable increment in germ cells number after 48 h treatment.Furthermore,FSH manifested a synergistic effect with E2 in stimulating germ cell proliferation.These results indicated that FSH might interact with estrogen to promote embryonic ovarian germ cell proliferation.FSH might exert its action by stimulating the synthesis of estrogen or expression of its receptors.

Follicle-stimulating hormone; Estrogen; Germ cell; Chicken embryo; Ovary

© Copyright 2004 Kunming Institute of Zoology, the Chinese Academy of Sciences
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