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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 26, No. 4, 2005, pp. 410-415
Bioline Code: zr05030
Full paper language: Chinese
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 26, No. 4, 2005, pp. 410-415

 en Antimicrobial Peptides Purified from Penus chinensis check for this species in other resources
AN Xian-hui, LV Yi1, LI Wei-guo, LIANG Jian-guo, XU Chun-hua, ZHANG Chong-xing

Abstract

Two antimicrobial peptides were purified from Penus chinensis check for this species in other resources by Sephadex G-50 gel filtration and reverse phase high performance liquid chromatography. The molecular weights were 1 071 and 1 311 Da respectively, determined by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. They inhibited the growth of Gram-positive and Gram-negative bacteria. The antimicrobial peptides strengthened the contractile response of isolated mice ileum. Serine proteases did not affect hydrolytic activities in our current experiments. These antimicrobial peptides play an important role in preventing microbial infection in P. chinensis.

Keywords
Penus chinensis, Antimicrobial peptide, Separation and purification

 
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