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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 28, No. 4, 2007, pp. 403-408
Bioline Code: zr07061
Full paper language: Chinese
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 28, No. 4, 2007, pp. 403-408

 en Temporal and Spatial Expression Patterns of Sox1 Gene in Xenopus laevis check for this species in other resources Embryo
MA, Li; ZHAO, Shu-hua; KONG, Qing-hua & MAO, Bing-yu


We describe the temporal and spatial expression pattern of Sox1 gene during Xenopus laevis early development and compare the expression patterns of Sox1-3 in the developing eye and brain. Alignment of Sox1-3 amino acid sequences shows a high conservation within the HMG-box DNA binding domains. RT-PCR analysis indicates that Sox1 is expressed throughout development from the unfertilized egg to at least the tadpole stage, although at different expression levels. The transcripts of XSox1 are detected in the animal pole at cleavage and blastrula stages and mainly in the central nervous system (CNS) and the developing eye at neurula stages. The study of the developmental expression of XSox1 will aid in the elucidation of the function of SoxB1 subgroup genes in vertebrate neurogenesis.

Sox1, Sox2, Sox3, Xenopus laevis, Expression pattern

© Copyright 2007 Kunming Institute of Zoology, the Chinese Academy of Sciences
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