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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 31, No. 1, 2010, pp. 43−49
Bioline Code: zr10007
Full paper language: Chinese
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 31, No. 1, 2010, pp. 43−49

 en Saccade: A Potential Diagnostic Tool and Drug Efficacy Test Criterion for Mental Disorders
Li, Hao; Hu, Xin-Tian & Ma, Yuan-Ye

Abstract

Saccades may play an important role in mental disorders research and diagnosis. Not only can saccade be used to help researchers to acquire the early and specific neuropathological changes, but also be a criterion of new drug development and drug efficacy tests. Abnormalities of saccadic eye movement appear in Parkinson’s disease, Alzheimer’s disease and major depressive disorder patients, but difficulties for its applications arise from unclear processes of neuropathological development and individual differences in patients. Establishing nonhuman primates’ model of mental disorders and monitoring saccadic parameters during the model construction will help us to overcome such difficulties.

Keywords
Saccade; Nonhuman primates’ model; Early mental disorders diagnoses; Drug efficacy test

 
© Copyright 2010 Kunming Institute of Zoology, the Chinese Academy of Sciences
Alternative site location: http://www.zoores.ac.cn/

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