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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 32, No. 1, 2011, pp. 91-96
Bioline Code: zr11014
Full paper language: Chinese
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 32, No. 1, 2011, pp. 91-96

 en Progress on nonhuman primate models of diabetes mellitus
Liang, Bin & Wu, Xiao-Yun

Abstract

Diabetes is the third most severely chronic disease after cardiovascular disease and cancer. World Health Organization (WHO) estimated 220 million diabetes patients worldwide in 2009. The rational animal models of diabetes are necessary for understanding the mechanisms of diabetes, diagnosis and prevention of diabetes as well as screen and evaluation of new drugs for diabetes treatment. Compared to other animal models of diabetes, the causes and symptoms of diabetes of nonhuman primates is more like human diabetes. We here reviewed the reported nonhuman primate models of diabetes based on the sources they were generated; especially focused on three models, Macaca mullata check for this species in other resources , M. fascicularis, Tupaia belangeri check for this species in other resources . Furthermore, we discussed the perspective development of nonhuman primate models of diabetes mellitus.

Keywords
Diabetes, Animal models of nonhuman primates, Macaca mullata, Macaca fascicularis, Tupaia belangeri

 
© Copyright 2011 Kunming Institute of Zoology, the Chinese Academy of Sciences
Alternative site location: http://www.zoores.ac.cn/

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