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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 32, No. 1, 2011, pp. 104-108
Bioline Code: zr11016
Full paper language: Chinese
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 32, No. 1, 2011, pp. 104-108

 en Progress on establishment of tree shrew ( Tupaia check for this species in other resources ) chronic infection with HBV in vivo
Li, Yuan; Su, Jian-Jia; Yang, Chun; Cao, Ji; Ou, Chao; Liang, Liang; Yang, Fang & Wang, Qi


Hepatitis B virus (HBV) infection is one of the important health problems worldwide, especially in China. Feasible and effective animal models of HBV infection in vivo are prerequisite for the HBV-related basic and clinical studies. Located in the highly prevalent region of HBV and hepatocellular carcinoma (HCC), the laboratoryof Guangxi Cancer Institute has focused on the cause, pathogenesis and chemoprevention of HCC, and has started the work of establishing tree shrew ( Tupaia check for this species in other resources ) models of HBV infection in vivo since the early 1980s. This paper provides an overview of the research process, and highlights the new progress on the chronic infection of tree shrews after inoculated with HBV neonatally in vivo.

Tree shrew (Tupaia), Animal model, Hepatitus B Virus

© Copyright 2011 Kunming Institute of Zoology, the Chinese Academy of Sciences
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