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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 35, No. 3, 2014, pp. 163-169
Bioline Code: zr14017
Full paper language: English
Document type: Research Article
Document available free of charge

Zoological Research, Vol. 35, No. 3, 2014, pp. 163-169

 en Animal models to study Mycobacterium tuberculosis check for this species in other resources and HIV co-infection
GUO, Ming & HO, Wen-Zhe

Abstract

Mycobacterium tuberculosis check for this species in other resources ( M.tb) and human immunodeficiency virus (HIV) co-infection has become a public health issue worldwide. Up to now, there have been many unresolved issues either in the clinical diagnosis and treatment of M.tb/HIV co-infection or in the basic understanding of the mechanisms for the impairments to the immune system by interactions of these two pathogens. One important reason for these unsolved issues is the lack of appropriate animal models for the study of M.tb/HIV co-infection. This paper reviews the recent development of research on the animal models of M.tb/HIV co-infection, with a focus on the non-human primate models.

Keywords
HIV; Mycobacterium tuberculosis; Co-infection; Animal model

 
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