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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 38, No. 3, 2017, pp. 127-137
Bioline Code: zr17017
Full paper language: English
Document type: Review Article
Document available free of charge

Zoological Research, Vol. 38, No. 3, 2017, pp. 127-137

 zh 树鼩——作为一种新颖的非人灵长类实验疾病动物模型
Xiao, Ji; Liu, Rong & Chen, Ce-Shi


树鼩; 动物模型; 转基因; 疾病

 en Tree shrew ( Tupaia belangeri check for this species in other resources ) as a novel laboratory disease animal model
Xiao, Ji; Liu, Rong & Chen, Ce-Shi


The tree shrew (Tupaia belangeri) is a promising laboratory animal that possesses a closer genetic relationship to primates than to rodents. In addition, advantages such as small size, easy breeding, and rapid reproduction make the tree shrew an ideal subject for the study of human disease. Numerous tree shrew disease models have been generated in biological and medical studies in recent years. Here we summarize current tree shrew disease models, including models of infectious diseases, cancers, depressive disorders, drug addiction, myopia, metabolic diseases, and immune-related diseases. With the success of tree shrew transgenic technology, this species will be increasingly used in biological and medical studies in the future.

Tree shrew (Tupaia belangeri); Animal model; Transgenic; Disease

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