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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 40, No. 3, 2019, pp. 146-150
Bioline Code: zr19015
Full paper language: English
Document type: Review Article
Document available free of charge

Zoological Research, Vol. 40, No. 3, 2019, pp. 146-150

 en Specific function and modulation of teleost monocytes/macrophages: polarization and phagocytosis
Lu, Xin-Jiang & Chen, Jiong

Abstract

Macrophages exist in most tissues and play a variety of functions in vertebrates. Teleost fish species are found in most aquatic environments throughout the world and are quite diverse for a group of vertebrate animals. Due to whole genome duplication and environmental adaptation, teleost monocytes/macrophages possess a variety of different functions and modulations compared with those of mammals. A deeper understanding of teleost monocytes/macrophages in the immune system will not only help develop teleost-specific methods of disease prevention but will also help improve our understanding of the various immune mechanisms in mammals. In this review, we summarize the differences in polarization and phagocytosis of teleost and mammalian macrophages to improve our understanding of the various immune mechanisms in vertebrates.

Keywords
Teleost; Monocytes/Macrophages; Phagocytosis; Cytokine production; Comparative immunology

 
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