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Zoological Research
Kunming Institute of Zoology, Chinese Academy of Sciences
ISSN: 2095-8137
Vol. 41, No. 5, 2020, pp. 477-494
Bioline Code: zr20051
Full paper language: English
Document type: Review Article
Document available free of charge

Zoological Research, Vol. 41, No. 5, 2020, pp. 477-494

 en Breast cancer animal models and applications
Zeng, Li; Li, Wei & Chen, Ce-Shi

Abstract

Breast cancer is the most common malignancy in women. Basic and translational breast cancer research relies heavily on experimental animal models. Ideally, such models for breast cancer should have commonality with human breast cancer in terms of tumor etiology, biological behavior, pathology, and response to therapeutics. This review introduces current progress in different breast cancer experimental animal models and analyzes their characteristics, advantages, disadvantages, and potential applications. Finally, we propose future research directions for breast cancer animal models.

Keywords
Breast cancer; Animal models; Metastasis; Drug development

 
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