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Australasian Biotechnology (backfiles)
AusBiotech
ISSN: 1036-7128
Vol. 11, Num. 3, 2001, pp. 6-10
Untitled Document

Australasian Biotechnology, Vol. 11 No. 3, 2001, pp. 6-10

NEWS

Code Number: au01033

NEW GENE TECHNOLOGY ACT BEGINS OPERATING

The new Gene Technology Act 2000 came into operation on June 21, amid claims that multinational companies conducting trials in Australia, including Aventis and Monsanto, were 'sabotaging' the law by making last minute applications before the law came into effect to keep the locations of their trials secret.

The Act creates the new statutory position, the Gene Technology Regulator, although no appointment has yet been made. A new website for the Office of the Gene Technology Regulator (http://www.ogtr.gov.au) has been established to disclose projects involving GMOs, but at the time of going to press the site was not operational.

The Act requires companies which seek commercial-in-confidence to prove that the value of confidentiality outweighs public interest, or that public knowledge of trial sites would pose a public health or safety risk. The Regulator can impose fines of up to $1.1 million per day for breach of the Act.

A Gene Technology Ministerial Council is to be established under the Act, and an intergovernmental agreement to establish the Council is currently being circulated to the States for their signature. The Council will have the power to determine policy principles under which the Gene Technology Regulator must operate.

The States are at various stages in developing complementary legislation to create a nationally consistent scheme.

The Tasmanian Government has tabled its Gene Technology Bill 2001 but is maintaining its moratorium on GMOs through the Plant Quarantine Act until a final policy is developed following the completion of reports by an independent Experts Group and the Joint House Select Committee late this month.

 

AUSTRALIAN BIOTECHNOLOGY REPORT

Ernst & Young and Freehills will join forces with the Commonwealth Government to produce the Second Australian Biotechnology Report.

The report, first published in 1999 by Ernst & Young and the Department of Industry, Science and Resources, set a benchmark in terms of identifying Australia's performance in the biotechnology industry. The second report will table the first analysis of Australia's progress and direction since the landmark 1999 publication.

According to James Cherry, partner with the biotechnology group at Freehills, the new report will have a broader focus and include companies and organisations associated with the biotechnology industry, such as medical device companies.

The report will be launched in June.

For more information, contact James Cherry, Partner, Freehills, Tel: (03) 9288 1596 or 0419 877 893

IAN GUST JOINS GENETIC TECHNOLOGIES

Genetic Technologies Limited has announced the appointment of one of Australia's most eminent scientists, Professor Ian Gust AO, to the Board of Directors.

Professor Gust is internationally known for his work on the hepatitis viruses and blood-borne infections, and has played a major role in Australia's rapid and effective response to the threat of AIDS.

Professor Gust is currently based at the University of Melbourne, Department of Microbiology and Immunology. He also serves as a scientific adviser to the Bill and Melinda Gates Children's Vaccine Program, the International AIDS Vaccine Initiative and the World Health Organisation.

CLUNIES ROSS NATIONAL SCIENCE & TECHNOLOGY AWARD

Nominations are now open for the Clunies Ross National Science & Technology Award 2002. The closing date for nominations is 20 July 2001.

Now in their tenth year, these Awards recognise and honour people who have made important contributions to science and its application for the economic, social or environmental benefit of Australia.

The Award aims to increase our community's knowledge and awareness of the achievements of Award recipients and their contribution to Australia http://www.cluniesross.org.au

DRAFT GUIDELINES FOR BIOTECHNOLOGY INNOVATION FUND

The Biotechnology Innovation Fund (BIF) is a new Federal Government program which aims to increase the rate of commercialisation of Australian biotechnology ventures by reducing the cost of demonstrating "proof of concept" for new biotech initiatives.

The program aims to address the critical gap between the research and commercial stages of development, where it can be difficult for companies to source funds to prove the viability of a new concept. By part funding technical testing and product analysis at this pre-seed stage, the program aims to increase the flow of Australian biotechnology projects proceeding to commercialisation .

Where applications meet the programs eligibility criteria, the program will fund up to 50% of the costs of establishing efficacy or proof of principle, to a maximum individual grant of $250,000.

Draft guidelines are now available on the Biotechnology Australia web site: http://www.biotechnology.gov.au/Industry_Research/BIF/BIF

Due to configuration problems with the server software, the direct link to the guidelines does not work. However, going to the BIF page (see below) and following the link to the guidelines does work. http://www.biotechnology.gov.au/industry_research/bif/

AUSTRALIAN BIOTECHNOLOGY DIRECTORIES ON THE WEB - A CALL TO UPDATE

A reader has asked us to advise members that several important biotechnology companies are currently not listed on the web-located 'Australian Biotechnology Directory'. This Directory was a joint venture of the Federal Department of Industry, Science and Resources and the Australian Biotechnology Association (ABA). However, it is located on the Department's webserver and it is maintained by the Department and not the ABA at the present time. All additions to the Directory, and updating of entries is handled by the Department.

We therefore call on all biotech companies to check their entry in the Directory and take steps to add to it or modify it if necessary. It is important that Australia has a comprehensive, searchable, and current Directory, so please take the trouble to do this. It benefits everyone.

Readers are also advised to check our links to companies on our website (http://www.aba.asn.au). This is a very useful supplementary Directory source. Once again, we request you to check your link, or to contact AusBiotech to add a link to the Association's site.

NATIONAL QUARANTINE AWARDS CATEGORY: SCIENCE AND RESEARCH

The Biosecurity Team at the Victorian Department of Natural Resources & Environment has won the Science and Research category of the 2001 National Quarantine Awards. The Biosecurity Team was rewarded for its lead role in the development of diagnostic protocols and contingency plans to prevent and control plant diseases.

The National Quarantine Awards are designed to focus public attention on the importance of quarantine to our unique environment and Australian way of life. The awards recognise that quarantine is a shared responsibility and reward outstanding efforts in quarantine from a range of organisations and individuals.

This award recognised the work the Biosecurity Team has undertaken over the last five years to produce contingency plans to assist in the prevention and control of fire blight (Erwinia amylovora), Sharka disease (plum pox virus), Pierce's disease (Xylella fastidiosa) and potato spindle tuber viroid. Each of these has the potential to cause considerable crop losses and affect the livelihoods of communities.

NEW ALLIANCE ESTABLISHES APAF AS LEADING PROTEOMIC ENTERPRISE IN AUSTRALIA

The Australian Proteome Analysis Facility (APAF), housed at Macquarie University, has joined a major international proteomic alliance that will cement its lead in the commercialisation of proteomics in Australia.

APAF announced its partnership in the global Proteome Works System alliance between Bio-Rad Laboratories and Micromass, at the recent Human Proteome Project conference in Virginia, USA.

The ProteomeWorks system integrates a range of technologies to produce instruments that enable simple and quick protein discovery. The alliance between Bio-Rad and Micromass combines the strengths of the world industry leaders in protein separations, biopolymer mass spectrometry and bioinformatics. APAF will add its expertise as a hands-on, high-throughput proteomics lab to the alliance.

Facility Manager at APAF, Dr Brad Walsh, says "APAF has been working with ProteomeWorks for some time, contributing to the design and testing of some of the instrumentation for the ProteomeWorks system. We are very excited to strengthen what has been a longstanding successful working relationship with Bio-Rad and Micromass."

Proteomics is a term originally coined by Macquarie scientists to describe the study of proteins of humans, plants, animals and bacteria. Proteins provide the critical link between genes and disease - it is the proteins produced by genes that are responsible for all processes that occur within a cell.

For further information, contact Dr Brad Walsh on (02) 9850 6201.

ACADEMY STATEMENT ON STEM CELL RESEARCH

The Australian Academy of Science has released a position paper on human stem cell research, confirming its opposition to the use of reproducting cloning techniques to produce a human foetus, but recognising the potential value of stem cell therapies in treating major degenerative diseases.

The Academy's paper pointed out that under the current state of knowledge, it was still necessary to use embryonic stem cells.

"Adult stem cells cannot adequately substitute for ES cells in basic research concerned with developmental biology because important biological differences exist between embryonic and adult stem cells. However, research into adult stem cells should be encouraged, especially to permit rapid application of insights gained from study of ES cells, and because progress made in this area of research may inform the other."

The paper concluded that while it was appropriate to legislate to set limits on research practices, such as the cloning of human foetuses, the details of research practice should not be regulated. It proposed that a national panel should be appointed to advise on appropriate regulation, and that State laws should be reviewed to apply a more consistent application of national standards. http://www.science.org.au

ANITBIOTIC RESISTANCE STRATEGY TAKES SHAPE

The National Health and Medical Research Council (NHMRC) has established an Expert Advisory Group on Antibiotics (EAGA) to provide advice to government and regulatory agencies on antibiotic resistance following the release of the Federal Government's response last August to the Joint Expert Technical Advisory Committee on Antibiotic Resistance (JETACAR) Report.

JETACAR was set up in December 1997 to assess the scientific evidence linking the use of antibiotics in food producing animals and the emergence of antibiotic resistant bacteria. It reported in August 1999 that development and transmission of antibiotic resistance is a threat to human health, and established that transfer of antibiotic resistance from food producing animals to humans does occur.

In response to JETACAR, the Commonwealth has established the Commonwealth Interdepartmental JETACAR Implementation Group (CIJIG), chaired jointly by Professor John Mathews (Health and Aged Care) and Dr Angelo Valois (AFFA), and with membership drawn from the Commonwealth Departments of Health and Aged Care and Agriculture, Forestry and Fisheries and Commonwealth regulatory agencies. The role of this Commonwealth Group is to manage the government's implementation plans for the twenty-two recommendations of the June 1999 JETACAR report. These recommendations cover regulatory control, monitoring and surveillance, prevention of infection, education and communication, and the coordination of a national antibiotic resistance management program.

Some of the activities being undertaken by CIJIG member agencies, or planned for 2001, include: a summit to engage stakeholders in the implementation process; a scoping study on hospital-acquired infections in Australia; two workshops and a contract to investigate options for antibiotic resistance surveillance in Australia; development of a work plan with the EAGA; development of a national antibiotic resistance communication/education strategy; and meetings with industry groups to develop a cost-effective system of monitoring and auditing for antibiotic distribution and end use.

The role of the Expert Advisory Group on antibiotic resistance is to provide expert advice to the Commonwealth through CIJIG, state and territory governments, and Commonwealth statutory authorities, on measures to reduce the risks of antibiotic resistance.

Chaired by Associate Professor John Turnidge, the former chair of JETACAR, the 13-member group met for the first time on April 30 to discuss its work program.

In August last year, the Australian Health Ministers Council (AHMC) appointed the AHMC JETACAR Taskforce to monitor and report to the Minister for Health and Aged Care on the implementation of the Government's response to JETACAR. This group is scheduled to report to the Minister in July 2001.

The Agriculture and Resource Management Council of Australia and New Zealand (ARMCANZ) has appointed a similar Taskforce to monitor the JETACAR implementation from the animal industry perspective.

Amongst recent developments in implementing JETACAR, a surveillance workshop was held on May 4 to discuss the development of a draft national antibiotic resistance surveillance strategy. A second workshop on surveillance is to be held in August before the draft surveillance strategy is released for public consultation in October.

A National Summit on Antibiotic Resistance was held in Sydney on May 30 - 31 which addressed the five key elements for the proposed national antibiotic resistance management program: regulatory controls; monitoring and surveillance; infection prevention strategies; education; and research. It was be attended by stakeholders in health care, pharmaceutical and agricultural industries, educators and other interested parties.

CIJIG has asked EAGA to identify the top five R&D priorities for antibiotic resistance research for the next 3 years and these will be raised with the NHMRC Strategic Research Development Committee (SRDC). More detail on progress with implementation of the JETACAR report is available on the internet at http://www.health.gov.au/pubhlth/strateg/jetacar/index.html.

BRESAGEN CLONES PIG

SA-based biotechnology company, BresaGen Limited, has announced that it has successfully cloned a pig, in association with the Immunology Research Centre at St Vincent's Hospital Melbourne.

The pig is now five weeks old, has been weaned and is healthy and growing normally.

The program leader, Dr Mark Nottle, said the purpose of the cloning was first, to provide a means of improving the breeding of livestock with superior qualities and disease resistance, and second the potential supply of animal organs for transplantation into humans. This would require the breeding of pigs without a gene called the Gal gene which is present in pigs but absent in humans and is thought to be important in the rejection of pig organs in human transplantation.

A different technology was required to that used for Dolly the sheep, and used cells which had been frozen in liquid nitrogen for more than two years.

The St. Vincent's Hospital/ Bresagen research program in xenotransplant- ation has been funded by an R&D Syndicate and by Nextran Inc, a subsidiary of Baxter Healthcare. Commercialisation of this technology is expected to lead to significant royalty streams flowing to BresaGen.

VICTORIA SNARES SYNCHROTRON

The Victorian Government has pre-empted proposals under the the Commonwealth Government's Major National Research Facility program by announcing it will provide up to $100 million towards a $157 million synchrotron facility to be located on a site near the International Centre for Science, Technology and Emerging Industries announced recently by Monash University. The synchrotron will provide a key facility for the determination of the molecular structure of potential new drugs, providing an option for scientists who currently have to access synchrotrons in Japan or the US through the Australian Synchrotron Research Program.

Three other proposals for synchrotron facilities have been under development by consortia led by the NSW and Queensland Governments and by the Australian Synchrotron Research Program led by ANSTO which currently provides access to overseas synchrotron facilities.

Organisations supporting the Victorian project include CSIRO, Western Mining, Walter and Eliza Hall Institute, Rio Tinto, Ericsson Australia, Telstra, the Committee for Melbourne, the Victorian Employer's Chamber of Commerce and Industry, the Australia-Israel Chamber of Commerce and the Victorian Chamber of Mines.

Announcing the decision, the Victorian Treasurer and Minister for State Development, John Brumby, said that the Government had initially considered contributing $47 million to the consortium to compete for funding under the MNRF program, but on the basis of the level of support and the potential return had decided to proceed without Commonwealth funding.

Tenders will be called for construction of the synchrotron within the next few month and work will begin in 2001-02 with a completion date of 2005.

NEW APPOINTMENTS

Australian biotechnology R&D firm, AMRAD Corporation, has appointed Dr Sandra Webb as its new Chief Executive. Dr Webb is currently Executive Vice President of Global Development Services for CroMedica Global Inc., a global medicines development company based in North America. She will take up her appointment at AMRAD in August 2001.

*****

Bionomics Limited has appointedDr Tom Gonda, formerly of the Ludwig Institute for Cancer Research in Melbourne, to the position of Chief Scientist of the company. Dr Gonda is a molecular biologist with over 20 years experience of research into cancer and blood cell formation. Bionomics, headed by CEO, Dr Deborah Rathjen, currently has provisional patents for more than 100 genes related to breast cancer and epilepsy.

 

AusBiotech Office Bearers

President: Dr Peter Riddles (IMBCom) Tel: (07) 3365 7130; Fax: (07) 3365 7226; Email: p.riddles@IMBCom.com.au

Vice President: Dr John Ballard (GroPep Ltd) Tel: (08) 8354 7701; Fax: (08) 8354 7747; Email: john.ballard@gropep.com.au

Directors: Mr Scott Carpenter (Aventis CropScience Pty Ltd) Tel: (03) 9248 6833; Fax: (03) 9248 6605; Email: scott.carpenter@aventis.com

Dr Simon Carroll (Curtin University) Fax: (08) 9286 4938 Email: s.carroll@exchange.curtin.edu.au

Dr Shanny Dyer (Avax Aust Pty Ltd) Tel: (02) 8923 2614; Fax: (02) 8923 2525; Email: sdyer@avax.com.au

Dr David Irving (R&D, Biotech Australia) Tel: (02) 9928 8829; Fax: (02) 9928 8899; Email: David_Irving@bioaust.com.au

Dr Lyndal Thorburn (Advance Consulting & Evaluation) Tel: (02) 6297 2438; Fax: (02) 6297 2203; Email: lyndal@advanceconsulting.com.au

Dr David Tribe (Dept. Microbiology, Univ. Melbourne) Tel: (03) 8344 5703; Fax: (03) 9347 1540; Email: detribe@unimelb.edu.au

Dr Elane Zelcer (Thrombogenix) Tel: (03) 9827 6427; Fax: (03) 9824 0054; Email: ezelcer@connexus.net.au

Executive Director: Dr Tony Coulepis (AGC) Tel: (03) 9596 8879; Fax: (03) 9596 8874; Mobile: 0419 436 902

Company Secretary: Mr Peter Francis (Francis, Abourizk & Lightowlers) Tel: (03) 9614 5222

Secretariat: Mrs Anne Greig/Mrs Margaret Dorevitch Tel: (03) 9596 8879; Fax: (03) 9596 8874 Email: admin@aba.asn.au

Treasurer: Mr Alex Forsyth Tel: (03) 9905 9914; Mobile: 0419 308 838 Fax: (03) 9905 9911

Publications: Dr Martin Playne (Melbourne Biotechnology) Tel: (03) 9598 9818; Mobile: 0407 804 851 Email: mplayne@netspace.net.au

STATE BRANCHES

ACT Branch: Dr Lyndal Thorburn (Advance Consulting & Evaluation) Tel: (02) 6297 2438; Fax: (02) 6297 2203; Email: lyndal@advanceconsulting.com.au

NSW Branch: Dr Peter Gray (University of New South Wales) Tel: (02) 9385 2061; Fax: (02) 9313 6710; Email: p.gray@unsw.edu.au

Qld Branch: Dr Greg Harper (CSIRO Tropical Agriculture) Tel: (07) 3214 2441; Fax: (07) 32142480 Email: gregory.harper@taq.csiro.au

Vic Branch: Mr Scott Carpenter (Aventis) Tel: (03) 9248 6833; Fax: (03) 9248 6605; Email: scott.carpenter@aventis.com

WA Branch: Professor Simon Carroll (Western Australian Biomedical Research Institute) Tel: (08) 9266 4822; Fax: (08) 9266 2342 Email: simon.carroll@exchange.curtin.edu.au

INTEREST GROUPS:

  Fermentation & BioProcessing Interest Group (FBIG): Dr John Power (RMIT University), Chairman Tel: (03) 9925 2796; Fax: (03) 9662 3421 Email: power@rmit.edu.au

Dr Nick Kotlartski (Alpharma Pty Ltd), Secretary Tel: (03) 9388 0655; Fax: (03) 9388 1259 Email: Nick.Kotlarski@alpharma.com.au

 

Access to the Celera Genetics Database

Would Access to the Celera Database Accelerate Your Research Effort?

Problem: The NH&MRC have secured access to the Celera Genomics Database for academic and "not-for-profit" research institutions around Australia - however there is no such accommodation made for Australia's commercially oriented biotechnology companies. This is a competitive disadvantage for Australian-based biotechnology companies that carry out research in genomics.

Solution: Assemble a Consortium of Australian Companies that will be able to negotiate with Celera as a single entity to provide access to the database for the Consortium members.

Some parameters of the proposed consortium and the agreement with Celera:

  • Membership will involve payment of an annual fee (to be determined).
  • Member companies will have full access to the database and their own private account.
  • All intellectual property generated through use of the database will remain the sole property of the member company.
  • The Consortium will be a not-for-profit entity - its primary mission is to coordinate access to the database for Australian biotechnology companies.
  • Celera have indicated they are willing to negotiate an agreement with a Consortium as described here.

If you responded "YES" to the above question, then we would like to invite you to register your expression of interest in joining the Australian Biotechnology Consortium. Please fill in the following section and send, email or fax it back to Hoki Beckham-Sionetali using the details below.

Contact Name: ___________________________________

Company: ___________________________________

Address: ___________________________________

__________________________________________________

Tel: (___) _________________ Fax: (___) _______________

Email: ____________________________________________

Send (by 6th July, 2001) to Hoki Beckham-Sionetali , International Diabetes Institute, 336 Glenferrie Rd, Malvern. Victoria 3144. Tel: 03-9244 5061 Fax: 03-9244 5311 Email: hokib@idi.org.au

Jeremy B. M. Jowett, Director of Genetics Research, International Diabetes Institute/Autogen Ltd.

Copyright 2001 - AusBiotech

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