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Indian Journal of Dermatology, Venereology, Leprology, Vol. 70, No. 1, January-February, 2004, pp. 54-56 Table Drug interactions of some commonly used drugs in dermatology Cyriac MJ Department of Dermatology and Venereology, Medical College, Kottayam Code Number: dv04018 Drug interactions leading to serious adverse effects are to be cautiously watched for when multiple drugs are used simultaneously.[1] It is important for the physician to be aware of these interactions. Although in many instances the adverse interaction does not reach a magnitude of recognizable clinical expression, rarely it can result in a serious adverse outcome. Adverse drug interactions may lead to increased toxicity, decreased efficacy or both. The possibility of interaction with non-prescription drugs, herbal or alternative medicines or food should also be borne in mind.[2] Increased risk of drug induced toxicity or therapeutic failure can occur when a new drug is added to a treatment regimen. It is impossible to remember all possible drug interactions. A ready to refer checklist is useful as a handy reference. Some of the commonly used drugs in dermatology and their interactions, resultant clinical effect and possible underlying mechanisms are given in [Table - 1], [Table:1contd]. [Table - 2] lists the drugs with their relative risk for inducing interactions. REFERENCES
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