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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323 EISSN: 0973-3922
Vol. 70, Num. 3, 2004, pp. 186-186
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Indian Journal of Dermatology, Venereology, Leprology, Vol. 70, No. 3, May-June, 2004, pp. 186
Letter To Editor
Silver sulphadiazine for MRSA infections
Tehrani Rustom
Consultant Dermatologist, Mallya Hospital, Bangalore
Correspondence Address:11 Plain Street, Shivajinagar, Bangalore
- 560001 rustomtehrani@yahoo.co.in
Code Number: dv04063
Sir,
In response to the article on methisillin resistant Stophylococcus (MRSA),[1] no
account will be complete without a mention of a medication which has
been in use for the last 30 years, and which has saved more lives than
all the other topical preparations put together - silver sulphadiazine
cream. Although primarily used in burns, it has been used in herpes zoster
and in toxic epidermolysis. It is useful in multi-drug resistant bacteria
along the entire spectrum, from MRSA to Pseudomonas aerogenesa.[2]
As compared to mupirocin, silver sulphadiazine cream has the following advantages:
- It is very inexpensive.
- While mupirocin comes in a 10 gram tube, silver sulphadiazine
is also available in a 1 kilogram jar.
- Mupirocin is available in a greasy ointment base while silver
sulphadiazine comes in a water washable base.
- Silver sulphadiazine is used both for treatment and prevention.
A combination of silver sulphadiazine and chlorhexidine, available in several brand names in India is more potent than silver sulphadiazine alone.[3]
REFERENCES
| 1. | Sachdev D, Amladi S, Natraj G, Baveja S, Kharkar V, Mahajan S, et al. An outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infection in dermatology indoor patients. Indian J Dermatol Venereol Leprol 2003;69:377-80. Back to cited text no. 1 |
| 2. | Wright JB, Lam K, Burrel RE Wound management in an era of increasing antibiotic resistance-a role for topical silver treatment. Am J Infec Control 1998;26:572-7. Back to cited text no. 2 |
| 3. | Fraser JF, Bodman J, Sturgess R, Faoagali J, Kimble RM. An vitro study of the antimicrobial efficacy of a1% silver sulphadiazine and a 0.2% chlorhexidine cream and a silver coated dressing. Burns 2004;30:35-41. Back to cited text no. 3 [PUBMED] [FULLTEXT] |
Copyright 2004 - Indian Journal of Dermatology, Venereology, Leprology
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