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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323 EISSN: 0973-3922
Vol. 71, Num. 6, 2005, pp. 444-446
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Indian Journal of Dermatology, Venereology and Leprology, Vol. 71, No. 6, November-December, 2005, pp. 444-446
FOCUS
Sebumeter
Pande SushilY, Misri Rachita
Department of Dermatology, Seth GS Medical College and KEM Hospital, Parel, Mumbai
Correspondence Address:Department of Dermatology, Seth GS Medical
College and KEM Hospital, Parel, Mumbai-400012, sushil_pande2003@rediffmail.com
Code Number: dv05148
Excess oiliness or excess dryness affects cosmetic appearance of the skin. Hence, estimation of oiliness is important to decide on the correct regimen to achieve cosmesis. Besides, sebum affects the permeability of skin and absorptivity of water, protects against bacteria and fungi, limits evaporation and affects permeation of pharmaceutical preparations and other active or non-active substances.
Hence measurement of natural presence of sebum on human skin particularly
facial skin is a matter of current interest amongst dermatologists and
pharmaceutical and cosmetic manufacturers.
Heterogenous components of sebum are produced from secretion of sebaceous
glands, fat of keratinous layer and remnants of perspiration.[1] Sebum
is a complex and variable mixture of lipids like glycerides, free fatty
acids, wax esters, squalene, cholesterol esters, and cholesterol.
Methods of sebum estimation
Many methods have been used in the past for collecting lipids from
human skin and measuring their production.[2] They
include swabbing by pads soaked in organic solvents such as hexane or ether,[3] washing
lipid solvents over areas of skin circumscribed by rings or caps.[4] Strauss
and Pochi devised a simple, reproducible but time consuming method for
measuring human sebaceous secretion. They placed a pad of absorbent cigarette
papers for 3 hrs on a delimited area of forehead and then extracted the
sebum with diethyl ether.[5],[6]
Antoine invented the sebumeter, which when placed on the skin displays
a qualitative or quantitative reading of skin oiliness.[7]
Facial skin is usually classified as dry, normal and oily. However skin
type does not match the amount of sebum secreted. Thus, simple and subjective
classification is of very limited use and it should be re-evaluated by
using an objective and standardized measuring tool like sebumeter.[8] It
is a device by which sebum can be quantified from any area of skin in an
objective manner.[9]
Different types of apparatus exist for measuring the amount of sebum. They
are based on the principle that when sebum is deposited on a translucent
element, such as a frosted glass or plastic plate or strip, the element
becomes increasingly transparent (greater the amount of sebum applied,
the greater the transparency produced).[10] Light
passing through this sebum covered translucent element is then measured
using photoelectric receiver.
Mechanism of sebum measurement by sebumeter
The measurement is based on the principle of grease-spot photometry [Figure - 1].
The measuring head of the cassette with its special tape is placed on the
skin. It is then inserted into a slot of the device, where the transparency
is measured by a light source passing through the tape. A photocell measures
the transparency. A microprocessor calculates the result, which is shown
on the display in mg sebum/cm2 of the skin.
Sebumeter probe (Cassette)
The Sebumeter-cassette contains a matt synthetic tape, 0.1 mm thick.
The measuring head of the cassette exposes a 64 mm2 section of the tape,
which is transported forward by a trigger at the side of the cassette for
the next measurement. The measuring time of 30 seconds is controlled by
a clock set in the device. Sebum is then determined as explained in the
measurement principle above. The instrument has an accuracy of ± 5%.
The reading of sebum may be displayed as a number or as type of skin i.e.
Dry; Dry/Normal; Normal; Normal/Oily; Oily.
Uses of sebumeter
- To classify skin type as dry, normal and oily in an objective
manner
- To prescribe pharmaceuticals/ cosmetics suitable to the patient′s
skin type to increase efficacy and minimize side effects
- Pre-placement examination for correct analysis of skin type in
the field of occupational medicine e.g. person of dry skin type may
not suitable
to work in chemical industry involving use of acid and alkalies
- To make early diagnosis of senile asteotosis
- To measure skin-cleaning effects of soaps[11]
- To do preliminary screening and follow up of patients with hyper-androgenic
states[12]
- To study the endocrine control of sebaceous follicle in women for
assessing hormonal ageing[13]
- To study the correlation between ′bad hair days′(days
during which most women find their hair difficult to manage), sebum secretion,
and menstrual cycle[14]
- To study sebo-suppressive effects of certain anti-acne medications
like retinoic acid in treatment of acne vulgaris[15]
- To study the sebaceous gland activity in diabetics, in whom, the
activity of the glands is decreased[16]
Pros and cons of using a sebumeter
Sebumeter is a simple and quick (requires less than a minute) method
of sebum estimation. The instrument is portable and its use requires little
training. The only disadvantage is the cost of the instrument as well as
the consumable viz., the cassette. Thus with increasing emphasis on skin
enhancement, sebumeter is likely to become a common implement in dermatologist′s
office[21].
References
1. | Sheu HM, Chao SC, Wong TW, Yu-Yun Lee J, Tsai JC. Human skin surface lipid film: an ultrastructural study and interaction with corneocytes and intercellular lipid lamellae of the stratum corneum Br J Dermatol 1999;140:385-91. Back to cited text no. 1 |
2. | Ebling FJ. Sebaceous glands. In: Marzulli FN, Maibach HI, editors. Dermatotoxicology and pharmacology. Washington DC: Hemisphere Publishing Corporation; 1977. p. 55-92. Back to cited text no. 2 |
3. | Cotterjill JA, Cunliffe WJ, Williamson B. A semiquantitative method for the biochemical analysis of sebum. Br J Dermatology 1971;85:35-9. Back to cited text no. 3 |
4. | Downing DT, Strauss JS, Pochi PE. Variability in the chemical composition of human skin surface lipids. J Invest Dermatol 1969;53:322-7. Back to cited text no. 4 |
5. | Strauss JS, Pochi PE. The quantitative gravimetric determination of sebum production. J Invest Dermatol 1961;36:293-8. Back to cited text no. 5 |
6. | Cunliffe WJ, Kearney JN, Simpson NB. A modified photometric technique for measuring sebum excretion rate. J Invest Dermatol 1980;75:394-8. Back to cited text no. 6 |
7. | Device and method for simple visual measurement of the amount of sebum present on human skin. http://www.freepatentsonline.com/5094248.html, last accessed 14-08-2005. Back to cited text no. 7 |
8. | Youn SW, Kim SJ, Hwang IA, Park KC. Evaluation of facial skin type by sebum secretion: discrepancies between subjective descriptions and sebum secretion. Skin Res Technol 2002;8:168-72. Back to cited text no. 8 |
9. | Kesseler T, Enderer K, Steigleder GK. Quantitative analysis of skin surface lipids using a sebumeter method. Random lipid levels on the skin surface during therapy with 13-cis-retinoic acid, minocycline hydrochloride and UVA rays. Z Hautkr 1985;1:857-65. Back to cited text no. 9 |
10. | CK Electronic, http://www.courage-khazaka.de/products/p_sm_815.htm, last accessed 14-08-2005. Back to cited text no. 10 |
11. | Wolf R, Friedmann M. Measurement of the skin-cleaning effects of soaps. Int J Dermatol 1996;35:598-600. Back to cited text no. 11 |
12. | Zlotogorski A, Glaser B, Bercovici B, Dikstein S. Sebum measurements for rapid identification of hyperandrogenism due to an ovarian Leydig cell tumor. Int J Dermatol 1991;30:276-7. Back to cited text no. 12 |
13. | Pierard-Franchimont C, Pierard GE. Postmenopausal aging of the sebaceous follicle: a comparison between women receiving hormone replacement therapy or not. Dermatology 2002;204:17-22. Back to cited text no. 13 |
14. | Birch MP, Messenger AG. 'Bad hair days', scalp sebum excretion and the menstrual cycle. J Cos Dermatol 2003;2:190. Back to cited text no. 14 |
15. | Anadolu RY, Sen T, Tarimci N, Birol A, Erdem C. Improved efficacy and tolerability of retinoic acid in acne vulgaris: a new topical formulation with cyclodextrin complex psi. J Eur Acad Dermatol Venereol 2004;18:416-21. Back to cited text no. 15 |
16. | Sakai S, Kikuchi K, Satoh J, Tagami H, Inoue S. Functional properties of the stratum corneum in patients with diabetes mellitus: similarities to senile xerosis. Br J Dermatol 2005;153:319. Back to cited text no. 16 |
17. | Pierard GE, Pierard-Franchimont C, Kligman AM. Kinetics of sebum excretion evaluated by the Sebutape-Chromameter technique. Skin Pharmacol 1993;6:38-44. Back to cited text no. 17 |
18. | CUDERM, http://www.cuderm.com/products_sebutape_rd.
php, last accessed 14-08-2005. Back to cited text no. 18 |
19. | CK Electronic, http://www.courage-khazaka.de/products/p_f_16.htm, last accessed 14-08-2005. Back to cited text no. 19 |
20. | Skin Analyzer SHP 88, http://www.conceptscom.net/jlauciis/skinanalyzer.shtml, last accessed 14-08-2005. Back to cited text no. 20 |
21. | Skin diagnostic SD 27, http://www.conceptscom.net/jlauciis/skindiag.shtml, last accessed 14-08-2005. Back to cited text no. 21 |
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