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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323 EISSN: 0973-3922
Vol. 75, Num. S1, 2009, pp. 4-4
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Indian Journal of Dermatology, Venereology and Leprology, Vol. 75, No. 7, , 2009, pp. 4
Acne in India: Guidelines for management - IAA Consensus Document
Genetics in acne
Raj Kubba, AK Bajaj, DM Thappa, Rajeev Sharma, Maya Vedamurthy, Sandipan Dhar, S Criton, Rui Fernandez, AJ Kanwar, Uday Khopkar, Malavika Kohli, VP Kuriyipe, Koushik Lahiri, Nina Madnani, Deepak Parikh, Sudhir Pujara, KK Rajababu, S Sacchidanand, VK Sharma, Jayakar Thomas - members Indian Acne Alliance
Correspondence Address: Dr.
Raj Kubba, Consultant Dermatologist, Kubba Clinic, 10, Aradhana Enclave,
Ring Road, New Delhi - 110066, India. rajkubba@hotmail.com
Code Number: dv09231
Although acne is not an inherited condition, there is an inherited predisposition. Several genes are believed to be involved, of which only the gene for cytochrome P-450-1A1 and the gene for steroid 21-hydroxylase are documented.[1] There is high concordance rate among identical twins. [2] XYY karyotype is associated with severe acne. [2] Positive family history of acne is obtained in 40% of patients [3] and correlates with more severe disease.
References
| 1. | Herane MI, Ando I. Acne in infancy and acne genetics. Dermatology 2003;206:24-8. Back to cited text no. 1 [PUBMED] [FULLTEXT] |
| 2. | Degitz K, Placzek M, Borelli C, Plewig D. Pathophysiology of acne. J Dtsch Dermatol Ges 2007;5:316-23. Back to cited text no. 2 |
| 3. | Cunliffe WJ, Gollnick HPM. Acne: Diagnosis and management. London: Martin Dunitz 2001. p. 1-46. Back to cited text no. 3 |
Copyright 2009 - Indian Journal of Dermatology, Venereology and Leprology
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