As head injury is an important cause of traumatic death, it is
essential to establish which clinical parameters available soon after injury
can be used to accurately predict outcome.
In an article published in the Archives of Surgery1, Texan
surgeons established determinants of mortality among patients with severe
blunt head injury, which, we believe have a bearing on practice of surgery in
Africa.
In a follow up study, they recruited patients with severe blunt head
injury, as defined by inability to follow commands, and prospectively entered
the data into a database.
The impact on survival of 23 potentially predictive parameters was studied
using univariate analysis. Logistic regression models were used to control
for confounding factors and to assess interactions between variables, whose
significance was determined by univariate analysis.
They found, by logistic regression analysis, that five risk factors were
independently associated with death. These included systemic hypotension on
admission, midline shift on the CT scan, intracranial hypertension, and
absence of pupillary light reflex. A low Glasgow Coma Scale score and
advanced age were found to be highly correlated risk factors that, when
combined, were independently associated with mortality.