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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905 EISSN: 1729-0503
Vol. 8, Num. 4, 2008, pp. 259-260
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Untitled Document
African Health Sciences, Vol. 8, No. 4, Dec, 2008, pp. 259-260
LETTERS TO THE EDITOR
Pioneer Human Open Heart Surgery using cardiopulmonary by
pass in Uganda
Akomea-Agyin C 1, Galukande
M2, Mwambu T3, Ttendo
S2, Clarke I 2
1 St. Anthony Hospital
London.2 International Hospital, Kampala (IHK), 3 Mulago Hospital Kampala
Correspondence author: Moses Galukande, P. O. Box 8177 Kampala, Uganda Email: mosesg@img.co.ug
Code Number: hs08054
Abstract
Introduction: For the first time in Uganda in April 2007, two open-heart surgeries were done using cardiopulmonary by pass.
A multidisciplinary team of largely indigenous Ugandans professionals working in Uganda formed the pioneering team.
Context: Access in cardiac surgery in the developing countries is very limited. The challenges that impede access to adequate
and appropriate health care including open-heart surgery are in the least complex and daunting.
Patient selection: Two 13 and 17 year old males with Secundum Atrial Septal defects were chosen from a long waiting list.
The criteria used included no or minimal co morbidity states, patient fitness and available ICU ventilation facilities.
Preparation: Took an eleven months period, including formulation and adoption of peri and intra operation protocols, training
of staff, sourcing of usable and mobilizing the financing.
Outcomes: The procedure for the two patients was successfully performed. The immediate and short-term postoperative
periods were uneventful. At the twelve months review point both patients were leading a normal life. In the months that followed 19
other open-heart procedures were done including two mitral valves replacements.
Conclusion: This program has greatly enhanced the level of care for the critically ill at this facility. Its sustenance and replication
in other centres in the country is essential. Government and development partners' support is critical. The educational value of
this program ought to be exploited by health professions students in the country.
Introduction
For the first time in Uganda on the
13th April and 15th April 2007, a multidisciplinary team at
International Hospital Kampala (IHK), Uganda carried out two
Open-heart surgery operations using a cardiopulmonary
by pass machine after an 11-month preparation
period. Closure of Atrial Septal Defects (ASD) in a 13 year
old and 17-year-old boys were done.
Cardiovascular disease is a growing threat
to health in Africa accounting for 9.2% of deaths in
2001 among which is Rheumatic valve disease as a
major contributor. Others include cardiomyopathy, stroke
and hypertension1, 2.
The average number of cardiac surgical
cases performed in North America, Australia and Europe
is 860 cases per million population. This means that in
an optimal environment where every patient who needs
a heart operation can actually get one, there will be
860 cases performed for every million population. On
the other hand, the average number of cardiac
cases performed in South America, the Russian
Federation, Asia and Africa is 60 cases per million population. This means that of all the people living outside
North America, Europe and Australia who actually need
an open-heart operation, 93% cannot get that operation.
In absolute numbers, this translates to 4.5 billion
people in the world having no access to cardiac surgery 3.
The challenges that impede access to
adequate and appropriate health care including open-heart
surgery are in the least complex and daunting. The health
care budget in Uganda is less than USD $ 15 per person
per year, life expectancy is less than 50 years. The burden
of infectious diseases is high and such takes up
most resources. The prevalence of HIV is 6.4% adults and
0.7 % children making more than one million people infected out of a population of only 30 million 4,5.
Numerous surgical teams travel
to underdeveloped countries to perform surgery each
year and to train the local surgeons and ancillary
personnel as best they can. However, in most such cases, the
surgical teams are present at those sites for no more than
one week per year, leaving the local populace and
surgeons to struggle for them selves for the remainder of
the year. The World Heart Foundation proposes that
rather than continuing with the current disorganized
and inefficient system, the problem should be addressed
by multi-dimensional approach directed at both an improvement in surgical services and an enhancement of education and training, taking maximum advantage
of contemporary communications technology and educational techniques but this proposal meets
steep organizational and logistical challenges.
Preparation
Despite the complex challenges posed, there is
hope for improvement of health care in Africa 6. Its in that spirit that the pioneering team took to a eleven
month preparatory period to make this feat possible in one
of the world's poorest countries.
A Paediatric cardiologist and a
cardio-thoracic surgeon (both Ugandan) did the patient screening.
The strategy was to start with Atrial Septal Defect without
or with minimal co-morbidities. Selection was based
on patient fitness, available ICU facilities for
ventilation, theatre consumables like cardiac cannulae and the
heart pulmonary by pass machine tubings. It was critical
that the first try-ever ends successfully with
satisfactory long-term outcomes, therefore the choice of
Atrial Septal Defect closure7. Routine infection
control measures were in place too. The post operative
records indicated a 0.2% annual post operation infection
rates for all general surgical cases at the facility in which
these pioneer surgeries were done.
The laboratory services available included
basic haematological, biochemical tests including
Arterial blood glasses, activated clotting time (with a turn
around time of less than 3-5 minutes). A 24/7 blood
bank service was available.
In the six bed ICU facility, two beds
and ventilators were dedicated to these patients.
Invasive monitoring was employed.
The team included two cardiac surgeons,
a general surgeon, an Intensivist, and several anaesthesiologists with support teams for
nursing, physiotherapy, and laboratory pharmacy and
biomedical technical departments. In the numerous
preparatory meetings, intra-operative procedure and
postoperative protocols were formulated and later referred to.
Outcomes
Pre cutting time preparations took 4 hours for the
first patient and 2 hours for the second. Operating time
was 4 hours for the first operation and two and half for
the second patient. Extubation in ICU for both
patients happened between 4-5 hours after the
operation. Discharge from intensive care unit was 48 hours
later with chest tubes and pacing wires removed and
incision site exposed.
All parameters Arterial Blood Gases,
X-ray, Echocardiogram, Full blood count; Urea and electrolytes, all vital signs BP were satisfactory
before both patients were discharged from ICU and later
from the hospital on day 9 and 11. Subsequent reviews
were done on an out patient basis, initially at
four-week intervals. Since then the program has carried on
with nineteen other operations including two
prosthetic valvular replacements.
Conclusion
This program has been a catalytic in up scaling the
level of care for the critically ill at International
Hospital Kampala.
We hope that the ripple on effect will
impact on the national strategies of improving specialist
Health Care Service delivery in Uganda. Recruiting
government and development partners' support is essential for
the sustenance of this program at this centre. The
educational value of this program should be exploited by
teaching institutions.
Acknowledgements
Khandaporov Edward, Nelson John F, Maureen Twikirize, Joy Agyin, Rachael Anuwo, Marianne
Calnan, Anna Botto, C. Tendo, Suzan Eleborat, Rose
Nanyonga, Irene Seguya, Ronald Nangamba, Cephas
Mijumbi, Margaret Okello, Joseph Ejoku, Peter Lwabi,
Pendo Galukande, Grace Nandaula, Veronica
Namaganda, Maureen Mpirirwe, ICU Nurses, Hope ward
Nurses, Nakasero Blood Bank, Uganda Heart Institute,
Cure Hospital Mbale, Biomedical dept and the IHK
senior management team
References
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