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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886 EISSN: 1998-4022
Vol. 57, Num. 1, 2009, pp. 98-99

Neurology India, Vol. 57, No. 1, January-February, 2009, pp. 98-99

Letter To Editor

Ruptured intracranial dermoid cyst

Department of Radiodiagnosis, KMC Hospital, Attavar, Mangalore - 575 001, Karnataka, India

Correspondence Address:Department of Radiodiagnosis, KMC Hospital, Attavar, Mangalore - 575 001, Karnataka, India

radiorai@gmail.com

Date of Acceptance: 21-Jan-2009

Code Number: ni09032

Sir

Intra-axial dermoid cysts are rare intracranial lesions, more so in the pediatric age group. Dermoid cysts account for about 0.2 to1.8% of all intracranial tumors and are commonly located in the cisternal spaces, mainly in the cerebellopontine angle and parasellar cisterns. [1] Intracranial dermoid cysts are pathologically characterized by a thick, stratified squamous epithelium cyst wall containing dermal elements. [2] Rupture of dermoid cyst can cause granulomatous chemical meningitis that can result in recurrent symptoms, most commonly headache. Headache is often the presenting feature of ruptured intracranial dermoid. Rupture of dermoid cyst is unusual to present in older people. [3]

Rupture of an intracranial dermoid produces a dramatic MR and CT appearance. [4] Computerized tomography (CT) scan typically shows a well-defined round hypodense mass lesion with attenuation consistent with fat and peripheral calcification [Figure - 1]. In case of ruptured dermoid cyst, CT scan shows low-density fatty droplets scattered throughout the ventricles and subarachnoid space [Figure - 2]. A fat-cerebrospinal fluid (CSF) level may also be seen. Dermoid cysts do not enhance on contrast administration. The presence of disseminated fat droplets in the subarachnoid space or ventricles on neuroimaging is diagnostic for a ruptured dermoid cyst. [5] A definitive diagnosis can be made by the characteristic features on CT scan [6] Magnetic resonance imaging typically demonstrates high signal intensities on T1 and variable signal intensities on T2. This is consistent with the lipid and cholesterol which typically collects within the dermoid cyst. When the cyst ruptures, high-signal droplets on T1 images may be seen scattered throughout the CSF. Sometimes a fat-CSF fluid level may also be seen.

References

1.Pant I, Joshi SC. Cerebellar intra-axial dermoid cyst: A case of unusual location. Childs Nerv Syst 2008;24:157-9.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]
2.Liu JK, Gottfried ON, Salzman KL, Schmidt RH, Couldwell WT. Ruptured intracranial dermoid cysts: Clinical, radiographic, and surgical features. Neurosurgery 2008;62:377-84.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Rajapakse A, Diack A. Ruptured intracranial dermoid: An unusual cause of headache in an older patient. Headache 2008;48:294-6.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]
4.Stephenson TF, Spitzer RM. MR and CT appearance of ruptured intracranial dermoid tumors. Comput Radiol 1987;11:249-51.  Back to cited text no. 4  [PUBMED]  
5.Das CJ, Tahir M, Debnath J, Pangtey GS. Neurological picture: Ruptured intracranial dermoid. J Neurol Neurosurg Psychiatry 2007;78:624-5.  Back to cited text no. 5  [PUBMED]  [FULLTEXT]
6.Amendola MA, Garfinkle WB, Ostrum BJ, Katz MR, Katz RI. Preoperative diagnosis of a ruptured intracranial dermoid cyst by computerized tomography: Case report. J Neurosurg 1978;48:1035-7.  Back to cited text no. 6  [PUBMED]  

Copyright 2009 - Neurology India


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