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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886 EISSN: 1998-4022
Vol. 59, Num. 4, 2011, pp. 652-653

Neurology India, Vol. 59, No. 4, July-August, 2011, pp. 652-653

Neuroimage

Pan-meningiomatosis in an operated case of cerebellopontine angle meningioma

Manoj Phalak, Vivek Tandon, Ashok K Mahapatra

Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address: Vivek Tandon, Department of Neurosurgery, Neurosciences Centre, AIIMS, Ansari Nagar, New Delhi, India, drtandonvivek@gmail.com

Date of Submission: 22-Apr-2011
Date of Decision: 24-Apr-2011
Date of Acceptance: 02-May-2011

Code Number: 11202

PMID: 21891965

DOI: 10.4103/0028-3886.84369

A 51-year-old lady was operated for right cerebello-pontine angle (CP angle) meningioma by suboccipital retromastoid approach about 3.5 years back. She presented at this admission with complains of progressive difficulty in swallowing and imbalance while walking since 8 months. Her family history was not positive for NF-2 nor any other possible etiology. She had right-sided cranial nerve palsies involving trigeminal to hypoglossal nerves with long tract signs. There was no evidence of neurocutaneous markers. Contrast magnetic resonance imaging of brain revealed diffuse meningeal thickening [Figure - 1]a-c. Meningeal thickening was more marked in both the CP angles and tentorium reaching up to the tentorial incisura. The patient was managed conservatively because no operative intervention was deemed suitable for such a diffuse disease.

In a study by Antinheimo et al., in the well-defined population, 1% of patients with meningioma had multiple meningiomas in association with NF2, and 4% had meningiomatosis without NF2. No families with meningiomatosis were found among the 823 patients with meningioma studied. [1] The various criteria described for NF2 clearly do not fit in our patient. [2] It is likely that contiguous growth and spread via CSF pathways may explain the diffuse meningiomatosis in our patient. [3]

References

1.Antinheimo J, Sankila R, Carpen O, Pukkala E, Sainio M, Jaaskelainen J. Population-based analysis of sporadic and type 2 neurofibromatosis-associated meningiomas and schwannomas. Neurology 2000;54:71-6.  Back to cited text no. 1    
2.Baser ME, Friedman JM, Wallace AJ, Ramsden RT, Joe H, Evans DG. Evaluation of clinical diagnostic criteria for neurofibromatosis 2. Neurology 2002;59:1759-65.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Nahser HC, Grote W, Lohr E, Gerhard L. Multiple meningiomas: Clinical and computer tomographic observations. Neuroradiology 1981;21:259-63.  Back to cited text no. 3    

Copyright 2011 - Neurology India


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