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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886 EISSN: 1998-4022
Vol. 59, Num. 5, 2011, pp. 794-795

Neurology India, Vol. 59, No. 5, September-October, 2011, pp. 794-795


Clinical spectrum of neurosyphilis in north east India

Beuy Joob1, Viroj Wiwanitkit2

1 Sanitation 1 Road Medical Academic Center, Bangkok, Thailand
2 Wiwanitkit House, Bangkhae, Bangkok, Thailand
Correspondence Address: Beuy Joob, Sanitation 1 Road Medical Academic Center, Bangkok, Thailand,

Code Number: ni11249

PMID: 22019688

DOI: 10.4103/0028-3886.86587


We read with great interest the article on neurosyphilis by Kayal et al. [1] They reported several clinical and laboratory findings in their study. In this study the diagnosis of neurosyphilis is based on the criteria proposed by Pope and Steiner, [2] not by the guidelines of the Center of Disease Control, which is the best tool for the diagnosis of neurosyphilis. [3],[4] However, the important test, Treponema-Palladiums Haemagglutination Test (TPHA), is not fulfilled in all the16 patients. Of interest, although this test is fulfilled, the positivity of TPHA is 98.3% in patients with neurosyphilis. [3]


1.Kayal AK, Goswami M, Das M, Paul B. Clinical spectrum of neurosyphilis in North East India. Neurol India 2011;59:344-50.  Back to cited text no. 1  [PUBMED]  Medknow Journal
2.Pope V, Steiner BM. Syphilis. In: Hiscox JA, editor. Topley and Wilson's microbiology and microbial infection, 10 th ed. New York: Wiley and Blackwell; 2007. p. 1838-64.  Back to cited text no. 2    
3.Luger AF, Schmidt BL, Kaulich M. Significance of laboratory findings for the diagnosis of neurosyphilis. Int J STD AIDS 2000;11:224-34.  Back to cited text no. 3    
4.Workowski KA, Berman S; Centers for Disease Control and Prevention (CDC). Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep 2010;59:1-110.  Back to cited text no. 4    

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