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Nigerian Journal of Physiological Sciences
Physiological Society of Nigeria
ISSN: 0794-859X
Vol. 22, Num. 1-2, 2007, pp. 89-91
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Nigerian
Journal of Physiological Sciences, Vol. 22, No. 1-2, 2007, pp. 89-91
Distribution of Abo and Rhesus Blood Groups in Abraka,
Delta State
E. I. Odokuma, A. C. Okolo And P.C. Aloamaka
Department
of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University Abraka Email;secretfiles1800@yahoo.com Tel no;0803 5658134.
Received: 24/7/2007
Accepted: 28/9/2007
Code Number: np07015
Summary
Blood group systems are determined
early in intrauterine life, specific to the individual and therefore significant
in management and identification. Seven hundred and ninety five volunteer
students of the Abraka campus of Delta State University were analyzed in this
4-year retrospective study. Amongst ABO system, blood group O was most common
followed by A, B and AB respectively. Rhesus positive was more common than
Rhesus negative in the rhesus system. Gender had no significant effect on both
blood group systems studied. In the combined ABO and Rhesus blood groups, O
positive was most common followed by A positive, B positive, AB positive O
negative and A negative respectively. This study documents ABO and Rhesus blood
group distribution patterns amongst south southern Nigerians. Findings will be
useful in maintaining a register of possible donors, for effective management
of medical emergencies.
Introduction
Several blood
group systems have been discovered but amongst the most important is the ABO
group (William, 1999). This system comprises antigens located on the surface of
red cells and some other body cells (William, 1999). It has been observed that
the serum of some individuals agglutinated red cells of other individuals
(Robert et al, 2000). Landstainer demonstrated four groups according to
antigens available A, B, AB and O and showed that an individual possessed
antibodies against those antigens he lacked on the red cell (Robert et al
2000). Several other red cell blood groups and hence antigens have been shown
(Edwards et al, 1995) but the rhesus group is another of utmost
importance (William, 1999). Cells which have Rhesus antigen on their surface
are described as Rhesus positive while those without this rhesus antigen are
Rhesus negative (Robert et al, 2000). Studies have shown variability
amongst racial and ethnic groups but close relationships however exist within
groups in these regions (Abdelaal et al, 1999). This study perhaps
documents for the first time, ABO and Rhesus blood group distribution in
Abraka. It will serve to provide information that is useful in emergency
situations where donors are required in absence of a functioning blood storage
facility.
Materials and
Methods
The study involved 795 students who were admitted
into the Delta State University Abraka campus for four consecutive years, 1999
to 2003. Data was obtained from the University Health center where ABO tests
are done routinely as part of the registration process. The technique involved
analyses of blood obtained by venupuncture (Michael, 1995). The ABO sampling
was carried out by the standard rapid tile method. This involved mixing one
volume of 20% of patients cells with one volume of commercially obtained antiA
and antiB sera respectively on an opal glass tile. The cells and sera in each
square were mixed and the tile rocked gently This was then viewed with the aid of
good light within two to five minutes and the presence or absence of
agglutination noted. This tile method was also used for the determination of
rhesus group using commercially obtained antiD sera as control (Dacie, 1995).
Approval for this investigation was given by the Research and Ethics Committee
of the Faculty of Basic Medical Sciences, Delta State University Abraka prior
to the commencement of this study.
Results
The gender distribution as depicted in
table 1 showed that 50.4 % and 49.4% of the subjects were female and male
respectively. Gender had no significant effect on the distribution of both
blood group systems studied (p>0.05) as shown in tables 2 and 3 (Falusi et
al, 2000). Blood group O was the most common (57.2%) followed by groups A 22%,
group B 18.7% and AB 2.1% (Table 1).
Table 1: Distribution of ABO blood
groups by sex
GENDER |
A |
B |
AB |
O |
TOTAL |
Female |
89 |
72 |
8 |
233 |
402 |
Male |
86 |
76 |
9 |
222 |
393 |
TOTAL |
175 |
148 |
17 |
455 |
795 |
Table 2: Distribution of
Rhesus blood groups by sex
GENDER |
Rh+ve |
Rh-ve |
NO OF STUDENTS |
Female |
393 |
9 |
402 |
Male |
388 |
5 |
393 |
Total |
781 |
14 |
795 |
In table 2, the relative percentages of
rhesus blood groups were shown. RhD was the most predominant (98%), while RhD
negative phenotype was 1.8%. In table 3, comparisons between rhesus and ABO
blood groups showed that O+ve was the most common of all the groups with a rate
of 56. 3%. This was followed by A+ve, 17%. A-ve was 6% and B-ve, 1%.
Individuals with O-ve blood are
described as universal donors owing to the absence of A, B and rhesus D
antigens on the surface of the red cells of these individuals. AB blood group
was the rarest of all the blood groups. These findings were similar to previous
studies in carried out in Nigeria (Onwukeme, 1990) . This is of
significance especially in emergencies where O-ve or AB blood types may be
required urgently. More so, students with O-ve blood should be counseled
especially as regards pregnancies where reactions may occur between RhD
antigens of the unborn child and the RhD antibodies of the mother (Sadler,
2000).
The study also showed a low frequency of
RhD negative phenotype. This finding was quite similar to that amongst African
subjects, West Indians and blacks living in Britain (Arneaud and Young, 1955,
Leck, 1969). The results are however in contrast to those obtained in Eastern highlands of Papua guinea where almost 100% of the population had RhD (Salmon et
al, 1988). It was also unlike in the Indians with a preponderance of RhD
negative phenotype 89.7% over the RhD gene of 10,3% (Thangaraj et al,
1992).
Table 3: Frequency distribution of ABO and Rhesus Blood
groups and Gender
GENDER |
A+ |
A- |
AB+ |
AB- |
B+ |
B- |
O+ |
O- |
TOTAL |
FEMALE |
85 |
4 |
8 |
- |
72 |
|
228 |
5 |
402 |
MALE |
84 |
2 |
9 |
- |
75 |
1 |
220 |
2 |
393 |
Total |
169 |
6 |
17 |
- |
147 |
1 |
448 |
7 |
795 |
%Total |
21.3% |
0. 7% |
2.1% |
- |
18.5% |
0.1% |
56.3% |
0.8% |
100% |
Conclusion
This study further confirms that blood group O was
the most common of the ABO blood group system in the population studied. AB
blood group was quite rare and Rhesus D was more common than Rhesus D negative phenotype.
No correlation was observed between gender, ABO and Rhesus blood groups. The
close similarity of blood group distributions in the African groups has also
been further emphasized.
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©Physiological Society of Nigeria, 2007
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