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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 90, No. 2, 1995, pp. 255-256
Bioline Code: oc95050
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 90, No. 2, 1995, pp. 255-256

 en Vaccination Against Schistosomiasis and Fascioliasis with the New Recombinant Antigen Sm14: Potential Basis of a Multi-Valent Anti-Helminth Vaccine?
Miriam Tendler; Monica Magno Vilar; Cristiana Alves Brito; Nicolau Maues Da Serra Freire; Naftale Katz & Andrew Simpson


Molecular cloning of components of protective antigenic 
preparations have suggested that related parasite fatty acid binding 
proteins could form the basis of the well documented protective, 
immune cross reactivity between the parasitic trematode worms Fasciola 
hepatica and  Schistosoma  mansoni
  check for this species in other resources
. We have now confirmed the cross 
protective potential of  parasite fatty acid binding proteins and
suggest that it may be possible to produce a single vaccine
that would be effective against at least two parasites, F. hepatica 
and S. mansoni of veterinary and human importance respectively.

schistosomiasis - fascioliasis - vaccines - fatty acid binding protein (FABP)

© Copyright 1995 Fundacao Oswaldo Cruz (Fiocruz)
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