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Australasian Biotechnology (backfiles)
AusBiotech
ISSN: 1036-7128
Vol. 11, No. 2, 2001, pp. 26-28
Bioline Code: au01026
Full paper language: English
Document type: Research Article
Document available free of charge

Australasian Biotechnology (backfiles), Vol. 11, No. 2, 2001, pp. 26-28

 en BIOPROCESSING - MICROBIAL BIOTRANSFORMATIONS: STEREOSELECTIVE SYNTHESIS OF PHARMACEUTICAL DRUG PRECURSORS
Shafiq Ahmad, Kylie Henderson, Geoff Dumsday and Michael Zachariou

Abstract

Biotransformations are becoming increasingly popular in the production of enantio- and regiopure- intermediates for synthesis of complex organic compounds. Whole microbial cells or enzymes can be used to carry out such specific chemical reactions that are otherwise difficult to achieve synthetically. Chemoenzymatic synthesis is of particular interest in the pharmaceutical industry where some steps can be carried out enzymatically to obtain chiral synthons for further enzymatic/chemical processing. In this report, we discuss some recent developments in the field together with a few examples.

 
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Alternative site location: http://www.ausbiotech.org/content.asp?pageid=16

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