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Australasian Biotechnology (backfiles)
ISSN: 1036-7128
Vol. 8, No. 3, 1998
Bioline Code: au98023
Full paper language: English
Document type: Research Article
Document available free of charge

Australasian Biotechnology (backfiles), Vol. 8, No. 3, 1998

 en DNA vaccines: Will they deliver?


Australasian Biotechnology,
Volume 8 Number 3, May/June 1998, pp. 153-159

DNA vaccines: Will they deliver?

Boyle JS, Agius CT, Lew AM1 and Barr IG

Code Number:AU98023
Sizes of Files:
Text: 37K
Graphics: Line drawing (gif) - 10K

A new form of vaccination using DNA as the vaccine instead of protein or attenuated pathogens has the potential to revolutionise the way vaccines are made and used. Based on administering purified plasmid DNA, these vaccines have shown remarkable promise in numerous animal models for the prevention of several important human diseases. The use of DNA as a vaccine raises several questions including the basic questions of just how do they work to stimulate an immune response, many of which we are only beginning to understand. In addition to efficacy, there are also several safety issues that will have to be addressed prior to large scale testing in humans. Given the excitement surrounding this new technology, the overriding question is whether they will deliver some or indeed any of their potential benefits to mankind.

Copyright 1998 Australian Biotechnology Association Ltd.


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