Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
Vol. 41, No. 2, 2004, pp. 92-95
Bioline Code: cn04017
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Cancer, Vol. 41, No. 2, 2004, pp. 92-95
© Copyright 2004 Indian Journal of Cancer.
Case Report - Glassy cell carcinoma of the uterine cervix a rare histology. Report of three cases with a review of the literature|
Deshpande ArchanaH, Kotwal MN, Bobhate SK
Glassy cell carcinoma is a poorly differentiated variant of adenosquamous carcinoma of the cervix associated with an aggressive course and a poor prognosis. We present three cases of glassy cell carcinoma of the cervix. Patients presented with a cervical growth which was biopsied. Histology the tumours showed nests of cells with a granular or clear cytoplasm, displaying marked pleomorphism and mitoses. Stroma showed an eosinophilic infiltrate. Two tumours showed a pure glassy cell pattern and one showed glandular differentiation with intracellular and extracellular mucin. Patients were treated with a combination of surgery, radiotherapy and chemotherapy but showed a poor response. Two patients died of the disease of pelvic or distant metastases within two years of diagnosis and one was lost to follow up. Although glassy cell carcinoma runs an aggressive clinical course, an early diagnosis may help in a more effective management and offer a better prognosis.
Cervical neoplasm, Glassy cell carcinoma
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