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Journal of Cancer Research and Therapeutics
Medknow Publications on behalf of the Association of Radiation Oncologists of India (AROI)
ISSN: 0973-1482 EISSN: 0973-1482
Vol. 3, No. 3, 2007, pp. 167-168
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Bioline Code: cr07043
Full paper language: English
Document type: Short Communication
Document available free of charge
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Journal of Cancer Research and Therapeutics, Vol. 3, No. 3, 2007, pp. 167-168
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Serum total glutathione-s-transferase levels in oral cancer
Prabhu, Krishnananda & Bhat, Gopalakrishna P.
Abstract
We conducted a study wherein serum total glutathione-s-transferase levels were measured in patients (n = 27) with various stages of biopsy proven oral cancer (squamous cell carcinoma) and age and sex matched healthy human volunteers (n=10). In all patients with oral cancer, serum total glutathione-s-transferase was measured before the onset of treatment. There was a significant increase in serum total glutathione-s-transferse levels in patients with stage IV oral cancer as compared to stage II (P = 0.001) and stage III (P = 0.002) oral cancer. This shows that alterations in serum total Glutathione-s-transferase levels may have a role in cancer progression.
Keywords
Glutathione-s-transferase, oral cancer, progression
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© Copyright 2007 Journal of Cancer Research and Therapeutics. Alternative site location: http://www.cancerjournal.net/
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