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Journal of Cancer Research and Therapeutics
Medknow Publications on behalf of the Association of Radiation Oncologists of India (AROI)
ISSN: 0973-1482
EISSN: 0973-1482
Vol. 4, No. 3, 2008, pp. 137-139
Bioline Code: cr08040
Full paper language: English
Document type: Case Report
Document available free of charge

Journal of Cancer Research and Therapeutics, Vol. 4, No. 3, 2008, pp. 137-139

 en Granulocytic sarcoma masquerading as Ewing's sarcoma: A diagnostic dilemma
Haresh, Kunhi Parambath; Joshi, Nikhil; Gupta, Chaitali; Prabhakar, Ramachandran; Sharma, Daya Nand; Julka, Pramod Kumar & Rath, Goura Kishor

Abstract

An eleven-year-old boy presented with a swelling in his left elbow. Radiologically the features were that of an Ewing′s sarcoma involving the ulna. Histopathology showed small round cell tumor strongly positive for Monoclonal Imperial Cancer research fund 2 (MIC2) antigen. Similar cells in the bone marrow were involved with MIC2 positivity. The patient developed skin lesions, which on biopsy were found to be chloromas. The initial biopsies were reevaluated with special stains revealing granulocytic sarcomas in acute myeloid leukemia masquerading as Ewing′s due to its MIC2 positivity. The possibility of myeloid neoplasms should be considered routinely with known MIC2 positive round cell tumors.

Keywords
Acute myeloid leukemia, chloroma, extra-medullary myeloid tumor, Ewing′s sarcoma, granulocytic sarcoma

 
© Copyright 2008 Journal of Cancer Research and Therapeutics.
Alternative site location: http://www.cancerjournal.net/

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