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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323
EISSN: 0378-6323
Vol. 71, No. 6, 2005, pp. 393-397
Bioline Code: dv05131
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Dermatology, Venereology and Leprology, Vol. 71, No. 6, 2005, pp. 393-397

 en A study of autologous melanocyte transfer in treatment of stable vitiligo
Pandya Vishvabhavan, Parmar KirtiS, Shah BelaJ, Bilimoria FE


Background: Replenishing melanocytes selectively in vitiliginous macules by autologous melanocytes is a promising treatment. With expertise in culturing melanocytes, it has now become possible to treat larger recipient areas with smaller skin samples.
Aim: To study the extent of repigmentation after autologous melanocyte transplantation in patients with stable vitiligo.
Methods: The melanocytes were harvested as an autologous melanocyte rich cell suspension from a donor split thickness graft. Melanocyte culture was performed in selected cases where the melanocyte cell count was insufficient to meet the requirement of the recipient area. These cells were then transplanted to the recipient area that had been superficially dermabraded.
Results: An excellent response was seen in 52.17% cases with the autologous melanocyte rich cell suspension (AMRCS) technique and in 50% with the melanocyte culture (MC) technique.
Conclusion: Autologous melanocyte transplantation can be an effective form of surgical treatment in stable but recalcitrant lesions of vitiligo.

Autologous melanocyte transplantation, Melanocyte culture, Melanocyte rich cell suspension

© Copyright 2005 Indian Journal of Dermatology, Venereology and Leprology.
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