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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323
EISSN: 0378-6323
Vol. 75, No. 1, 2009, pp. 63-67
Bioline Code: dv09015
Full paper language: English
Document type: Case Report
Document available free of charge

Indian Journal of Dermatology, Venereology and Leprology, Vol. 75, No. 1, 2009, pp. 63-67

 en Nephrogenic Fibrosing Dermopathy
Ragunatha, S.; Palit, Aparna; Inamadar, ArunC; Madraki, Ravindra M. & Yelikar, B.R.

Abstract

An adult female patient on hemodialysis for chronic renal failure presented with large, brownish, and indurated plaques with bound-down skin on both lower limbs and abdomen along with difficulty in movement of the legs. Histopathological features revealed thick collagen bundles admixed with mucin and intercalating spindle-like cells characteristic of nephrogenic fibrosing dermopathy (NFD). Immunohistochemical study showed prominent CD68 positivity and weak CD34 positivity suggesting that the plaques were more than 20-weeks old. NFD in patients with chronic renal failure of unknown cause is a poor prognostic indicator. Early detection before the development of contracture and prompt treatment of NFD and underlying renal failure may reverse this disabling condition.

Keywords
Nephrogenic fibrosing dermopathy, Nephrogenic systemic fibrosis, Dialysis, Renal failure

 
© Copyright 2009 Indian Journal of Dermatology, Venereology and Leprology.
Alternative site location: http://www.ijdvl.com

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