Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
Vol. 75, No. 4, 2009, pp. 394-397
Bioline Code: dv09125
Full paper language: English
Document type: Case Report
Document available free of charge
Indian Journal of Dermatology, Venereology and Leprology, Vol. 75, No. 4, 2009, pp. 394-397
© Copyright 2009 Indian Journal of Dermatology, Venereology and Leprology.
Primary systemic amyloidosis: Three different presentations|
Saoji, Vikrant; Chaudhari, Sanjiv & Gohokar, Dilip
Primary systemic amyloidosis is a rare disease. We report three cases of primary systemic amyloidosis, one case with multiple myeloma and two cases without any hematological abnormality. Purpuric lesions were the only presenting symptoms of the patient with multiple myeloma and only on investigation, myeloma was detected. Bone marrow biopsy and serum and urine electrophoresis were normal in remaining two cases. These two patients presented with typical waxy lesions on face. Cutis verticis gyrata was present in one case and carpal tunnel syndrome was seen in other case as an additional diagnostic clue. Macroglossia was present in all three cases. Diagnosis was confirmed in all three cases by biopsy using haematoxylin and eosin staining and Congo red staining. Polarized microscopy was not done because of unavailability.
Primary systemic amyloidosis, Myeloma, Idiopathic
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