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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 1, No. 2, 2004, pp. 1-2
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Bioline Code: gm04010
Full paper language: English
Document type: Research Article
Document available free of charge
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European Journal of General Medicine, Vol. 1, No. 2, 2004, pp. 1-2
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REVIEW ARTICLE - DEFINING A PHYSIOLOGICAL ROLE FOR THE TUBULIN TYROSINATION CYCLE
Haitham T. Idriss
Abstract
This paper proposes, based on data from other laboratories, that the physiological function of the tubulin tyrosination cycle is to maintain a check for normal physiological milieu within cells, whereby tyrosine and nitrotyrosine act as markers for normality and abnormality, respectively. Incorporation of nitrotyrosine is postulated to initiate apoptosis to facilitate elimination of abnormal cells.
Keywords
Tubulin tyrosination
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