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Indian Journal of Human Genetics
Medknow Publications on behalf of Indian Society of Human Genetics
ISSN: 0971-6866
EISSN: 0971-6866
Vol. 8, No. 2, 2002, pp. 66-68
Bioline Code: hg02013
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Human Genetics, Vol. 8, No. 2, 2002, pp. 66-68

 en Chromosomal Analysis in Recurrent Spontaneous Aborters
Lakshmi Kalpana V, Satyanarayana M, Prabahker S and Sarvani R.


A type of endomitotic chromosome reduplication in the interphase stage of cell cycle was found in lymphocyte cultures of couples with spontaneous abortions. To find out the presence of this anomaly chromosomal analysis was performed in a series of 20 women with repeated spontaneous abortions and their husbands. Demographic data was also collected from them. Out of 40 individuals, a 27 years male whose wife has experienced three spontaneous abortions was found to have Endoreduplication. His wife was normal with 46, XX chromosomal complement.

Endoreduplication, Spontaneous abortions, Endomitotic chromosomes, Interphase chromosomes, Consanguinity, Gestation period, DNA replication, Aneuploidy.

© Copyright 2002 - The Indian Society of Human Genetics
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