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Indian Journal of Human Genetics
Medknow Publications on behalf of Indian Society of Human Genetics
ISSN: 0971-6866
EISSN: 0971-6866
Vol. 18, No. 1, 2012, pp. 40-42
Bioline Code: hg12006
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Human Genetics, Vol. 18, No. 1, 2012, pp. 40-42

 en An anthropometric and hematological comparison of sickle cell disease children from rural and urban areas
Nikhar, H S.; Meshram, S U. & Shinde, G B.


Background: Sickle cell disease (SCD) is a prevalent genetic disorder in India and the rural and urban areas experience distinctly different healthcare facilities. In view of this, a comparative study of SCD-SS pattern children of age 8-15 years from rural and urban areas of Wardha district of Central India was carried out using anthropometric and hematological parameters.
Materials and Methods: The data were collected using standard methods and the results showed a significant (P < 0.05) difference in the mean values for body weight, body mass index (BMI), hemoglobin, hematocrit, and white blood corpuscles (WBC). Statistical analysis of the data was done using SPSS 18.0 software. Individuals were screened by solubility test method. Sickle cell patterns (AS and SS) were determined by using electrophoresis technique.
Result : The SCD-SS children from rural were significantly underweight than those from the urban area of Wardha district. BMI is a good indicator of nutritional status and BMI values of SCD children have less than desired.
Conclusion : The study highlights an urgent need to conduct integrated investigations for SCD population of rural areas covering clinical, nutritional, and social aspects.

Body mass index, hemoglobin, rural and urban area, sickle cell disease

© Copyright 2012 Indian Journal of Human Genetics.
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