About Bioline  All Journals  Testimonials  Membership  News

The Journal of Health, Population and Nutrition
ISSN: 1606-0997
EISSN: 1606-0997
Vol. 23, No. 4, 2005, pp. 305-310
Bioline Code: hn05041
Full paper language: English
Document type: Research Article
Document available free of charge

The Journal of Health, Population and Nutrition, Vol. 23, No. 4, 2005, pp. 305-310

 en Antibodies Among Healthy Population of Developing Countries Against Enterohaemorrhagic Escherichia coli check for this species in other resources O157:H7
Voravuthikunchai, Supayang Piyawan; Chaowana, Chitamas; Perepat, Prarin; Iida, Tetsuya & Honda, Takeshi


In Thailand, no reports are available on Escherichia coli check for this species in other resources serotype O157:H7, a causative agent of severe bloody diarrhoea, sometimes associated with haemolytic-uraemic syndrome and thrombotic thrombo-cytopenic purpura. The reason for the non-identification of infection due to E. coli O157 in this country and in other developing countries has not been rigorously discussed. The aim of this study was to determine the humoral response against the infectious organism. The IgM and IgG antibody responses against E. coli O157 lipopolysaccharide were studied using indirect enzyme-linked immunosorbent assay. Three hundred and thirty-two serum samples obtained from healthy blood donors and patients with diseases unrelated to diarrhoea were investigated. With a cut-off value of mean +2 SDs for each age-group, the frequency of the IgM and IgG responses to O157 lipopolysaccharide was 11.74% (39 of 332 samples) and 22.59% (75 of 332 samples) respectively. Furthermore, agglutination test of 173 subjects revealed titres ranging from 10 to 40 in all the samples. The results suggest possible exposure of the Thai population to cross-reacting antigens from other intestinal organisms in addition to infection due to E. coli O157:H7.

Escherichia coli, Enterohaemorrhagic; Escherichia coli O157:H7; Antibody formation; Immunity; Immune response: Haemolytic-uraemicsyndrome; Colitis, Haemorrhagic; Thrombotic thrombocytopenic purpura;Verocytotoxins; Thailand

© Copyright 2005 - ICDDR,B: Centre for Health and Population Research
Alternative site location:

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil