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The Journal of Health, Population and Nutrition
icddr,b
ISSN: 1606-0997
EISSN: 1606-0997
Vol. 24, No. 2, 2006, pp. 221-227
Bioline Code: hn06027
Full paper language: English
Document type: Research Article
Document available free of charge

The Journal of Health, Population and Nutrition, Vol. 24, No. 2, 2006, pp. 221-227

 en Electrocardiographic Abnormalities Among Arsenic-exposed Persons Through Groundwater in Bangladesh
Ahmad, Sk. Akhtar; Khatun, Fatema; Sayed, M.H. Salim Ullah; Khan, Manzurul Haque; Aziz, Md. Rashed; Hossain, Mohammed Zakir & Faruquee, M.H.

Abstract

This study was carried out among arsenic-exposed and non-exposed people of Bangladesh to assess and compare their cardiac status based on electrocardiographic (ECG) findings. For the purpose of the study, participants were included in three groups: arsenic-exposed persons with arsenicosis (arsenicosis group), arsenic-exposed persons without arsenicosis (non-arsenicosis group), and persons not exposed to arsenic (non-exposed group). Each group included 50 respondents. In this study, no significant difference in heart rate, rhythm, axis, and pulse rate interval was detected among the arsenicosis, non-arsenicosis and non-exposed groups. A significant difference in corrected QT interval between the arsenicosis and the non-exposed group (p<0.05) was observed. On the contrary, no statistically significant difference in corr-ected QT interval between the non-arsenicosis and the non-exposed group was found. Abnormal QRS complex was found among 14%, 8%, and 2% of the arsenicosis, non-arsenicosis, and non-exposed groups respectively. ECG findings, indicative of left ventricular hypertrophy, ischaemic heart disease, andright bundle branch block, were high among the arsenicosis group. Overall, abnormal ECG findings were high (58%) among the respondents of the arsenicosis group and were highly significant (p<0.001). The findings revealed that there was a significant association between ECG abnormalities and arsenic exposure.

Keywords
ECG; Corrected QT interval; QRS complex; Left ventricular hypertrophy; Ischaemic heart disease; Arsenicosis; Arsenic; Arsenic exposure; Cross-sectional studies; Bangladesh

 
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